DELLA functions evolved by rewiring of associated transcriptional networks.

Autor: Briones-Moreno A; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain., Hernández-García J; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain.; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., Vargas-Chávez C; Institut de Biologia Evolutiva (CSIC-U Pompeu Fabra), Barcelona, Spain., Blanco-Touriñán N; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain., Phokas A; School of Biosciences, University of Birmingham, Birmingham, UK., Úrbez C; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain., Cerdán PD; Fundación Instituto Leloir, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina., Coates JC; School of Biosciences, University of Birmingham, Birmingham, UK., Alabadí D; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain., Blázquez MA; Instituto de Biología Molecular y Celular de Plantas (CSIC-U Politècnica de València), Valencia, Spain. mblazquez@ibmcp.upv.es.
Jazyk: angličtina
Zdroj: Nature plants [Nat Plants] 2023 Apr; Vol. 9 (4), pp. 535-543. Date of Electronic Publication: 2023 Mar 13.
DOI: 10.1038/s41477-023-01372-6
Abstrakt: DELLA proteins are land-plant specific transcriptional regulators that transduce environmental information to multiple processes throughout a plant's life 1-3 . The molecular basis for this critical function in angiosperms has been linked to the regulation of DELLA stability by gibberellins and to the capacity of DELLA proteins to interact with hundreds of transcription factors 4,5 . Although bryophyte orthologues can partially fulfil functions attributed to angiosperm DELLA 6,7 , it is not clear whether the capacity to establish interaction networks is an ancestral property of DELLA proteins or is associated with their role in gibberellin signalling 8-10 . Here we show that representative DELLAs from the main plant lineages display a conserved ability to interact with multiple transcription factors. We propose that promiscuity was encoded in the ancestral DELLA protein, and that this property has been largely maintained, whereas the lineage-dependent diversification of DELLA-dependent functions mostly reflects the functional evolution of their interacting partners.
(© 2023. The Author(s), under exclusive licence to Springer Nature Limited.)
Databáze: MEDLINE
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