| Autor: |
Lauscher P; MUC Research GmbH, Munich, Germany., Hanhoff N; German Association of Physicians specialized in HIV Care (dagnae) e.V., Berlin, Germany., Valbert F; Institute for Healthcare Management and Research Duisburg-Essen, Essen, Germany., Schewe K; Infektionsmedizinisches Centrum Hamburg, Hamburg, Germany., Koegl C; MUC Research GmbH, Munich, Germany., Bickel M; Infektiologikum Frankfurt, Frankfurt, Germany., Hoffmann C; ICH Study Center, Hamburg, Germany., Stephan C; University Hospital Frankfurt am Main, Frankfurt, Germany., Pauli R; MVZ am Isartor, Munich, Germany., Preis S; ClinovateNET GmbH & Co KG, Munich, Germany., Neumann A; Institute for Healthcare Management and Research Duisburg-Essen, Essen, Germany., Wolf E; MUC Research GmbH, Munich, Germany. |
| Abstrakt: |
Delayed HIV diagnosis at advanced stages of disease remains common (33%-64%). This analysis of the multi-center FindHIV study including newly diagnosed HIV-infected adults in Germany, focused on the potential role of socio-demographic and psychological factors on late diagnosis (formerly "late presentation", AIDS diagnosis or CD4 cells <350/µL). These data were collected from patient profiles, physician-patient interviews and questionnaires. Participating centers ( n = 40) represented the diverse health care settings in HIV care and geographic regions. Of 706 newly diagnosed adults (92% male, median age 39 years) between 2019 and 2020, 55% (388/706) were diagnosed late with a median CD4 cell count of 147/µL; 20% (142/706) presented with AIDS. From the physicians' perspective, earlier diagnosis would have been possible in 45% of participants (late versus non-late presentation 58% versus 29%). The most common physician-perceived reason was an underestimated risk for HIV infection by the patient (37%). In multivariable logistic regression analysis, older age, sexual contacts with both sexes as possible route of HIV transmission, being married, and a poor level of knowledge about HIV treatment were found to be associated with a significantly elevated risk for late presentation. Education, employment status, sexual relations, migration background and personality traits were not. Trial registration : German Clinical Trials Register (DRKS00016351). |
