The Prevalence of Positive Donor Corneoscleral Rim Culture and its Association with Ocular Infection After Transplantation.

Autor:	Bolac R; Department of Ophthalmology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Türkiye., Vural ET; Department of Ophthalmology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Türkiye., Yildiz E; North American Lasik and Eye Surgery Center, Dubai, United Arab Emirates., Kaya G; Department of Ophthalmology, Gazipasa State Hospital, Antalya, Türkiye., Aksaray S; Department of Microbiology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Türkiye.
Jazyk:	angličtina
Zdroj:	Beyoglu eye journal [Beyoglu Eye J] 2023 Mar 01; Vol. 8 (1), pp. 50-54. Date of Electronic Publication: 2023 Mar 01 (Print Publication: 2023).
DOI:	10.14744/bej.2023.08931
Abstrakt:	Objectives: The aim of the study was to determine the prevalence of positive corneoscleral donor rim cultures and to report keratitis and endophthalmitis after keratoplasty. Methods: Eye bank records and medical records of patients who underwent keratoplasty between September 1, 2015, and December 31, 2019, were retrospectively reviewed. Patients who had routine donor-rim culture taken during surgery and followed up for at least 1 year in the post-operative period were included in the study. Results: A total of 826 keratoplasty procedures were performed. A total of 120 (14.5%) cases had a positive donor corneoscleral rim culture. Positive bacterial cultures were obtained from 108 (13.7%) of the donors. Bacterial keratitis was observed in one patient (0.83% of recipients) who had a positive bacterial culture. Positive fungal cultures were obtained from 12 (1.45%) donors, of whom one (8.33% of recipients) developed fungal keratitis. Endophthalmitis was observed in one patient whose culture result was negative. Both bacterial and fungal culture results were similar in penetrating and lamellar surgical procedures. Conclusion: Although the donor corneoscleral rims have a high positive culture result, the rate of bacterial keratitis and endophthalmitis is low, the risk of infection is high in patients with a fungal positive donor rim. Closer follow-up of patients with fungal positive donor corneo-scleral rim result and initiation of aggressive antifungal treatment when infection occurs will be beneficial. Competing Interests: Conflict of Interest: None declared. (Copyright: © 2023 by Beyoglu Eye Training and Research Hospital.)
Databáze:	MEDLINE
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