Testicular Regression Syndrome: Two Case Studies.
| Autor: | Elazizi L; Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR., Elazime Z; Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR., Lahmamssi FZ; Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR., Salhi H; Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR., Elouahabi H; Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Feb 08; Vol. 15 (2), pp. e34771. Date of Electronic Publication: 2023 Feb 08 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.34771 |
| Abstrakt: | Testicular agenesis, also called testicular regression syndrome (TRS), is a rare disease. It is defined by the complete absence of testicular tissue associated with a 46,XY karyotype. The phenotype is variable depending on when gonadal regression occurs in utero. Several etiologies have been identified. Here, we report two cases of TRS with an initial diagnosis of cryptorchidism and bilateral impalpable testes. The hormonal assessment showed an undetectable anti-Müllerian hormone (AMH) level and high gonadotropins. Also, radiological exploration did not show the testicles in a normal position, which was confirmed by a negative laparoscopy, establishing the diagnosis of TRS. Androgen replacement therapy along with psychological support to the patient is recommended is such cases. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Elazizi et al.) |
| Databáze: | MEDLINE |
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