Use of ozone therapy in Implant Dentistry: a systematic review.

Autor: Randi CJ; Specialization Course in Oral Implantology, Faculdade CTA, São Paulo, SP, Brazil., Heiderich CMC; Specialization Course in Oral Implantology, Faculdade CTA, São Paulo, SP, Brazil., Serrano RV; Graduate Dentistry Program, Ibirapuera University, São Paulo, SP, Brazil., Morimoto S; School of Dentistry, Department of Orthodontics and Pediatric Dentistry, University of São Paulo, São Paulo, SP, Brazil., de Moraes LOC; Department of Morphology and Genetics, Federal University of São Paulo, São Paulo, SP, Brazil., Campos L; Graduate Program in Implantology, School of Dentistry, University of Santo Amaro, São Paulo, SP, Brazil., Palma LF; Department of Pathology, Federal University of São Paulo, São Paulo, SP, Brazil. luizfelipep@hotmail.com.
Jazyk: angličtina
Zdroj: Oral and maxillofacial surgery [Oral Maxillofac Surg] 2024 Mar; Vol. 28 (1), pp. 39-49. Date of Electronic Publication: 2023 Mar 13.
DOI: 10.1007/s10006-023-01149-3
Abstrakt: Purpose: Ozone is a potent antioxidant agent which presents an important antimicrobial action and many other biological effects. Although ozone therapy has been widely described and summarized in several other Dentistry areas recently, the studies concerning Dental Implantology have not been systematically compiled and evaluated. Thus, the present study aimed to evaluate the effectiveness of ozone therapy in dental implant procedures.
Methods: MEDLINE (via PUBMED), Cochrane Central Register of Controlled Trials (CENTRAL), and OpenGrey databases were searched (up to, and including, January 23, 2023) for studies in the English language. In addition, the reference lists of the articles were manually examined. Only interventional studies (controlled clinical trials, randomized or not) were considered eligible for inclusion. The risk of bias in each included study was assessed using the Cochrane tool for assessing risk of bias in randomized trials - version 2.
Results: 71 potentially eligible records were retrieved but only 5 articles were evaluated and considered eligible for inclusion. Among the studies, 2 addressed clinical situations related to implant insertion, and 3 involved pathological conditions affecting implants in function. Furthermore, only one randomized clinical trial was categorized as low risk of bias.
Conclusion: The adjuvant use of ozone therapy may positively affect some outcomes in Implant Dentistry, both in treating pathological conditions and conducting rehabilitation (implant installation, secondary implant stability). However, as most studies have a high risk of bias and high heterogeneity, a definitive conclusion cannot be drawn.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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