One-pot facile synthesis of hexagonal Bi 2 Te 3 nanosheets and its novel nanocomposites: Characterization, anticancer, antibacterial, and antioxidant activities.

Autor: Nour A; Composites and Nano-Structured Materials Research Department, Advanced Technology and New Materials Research Institute, City of Scientific Research and Technological Applications, P.O. Box 21934, New Borg El-Arab, Alexandria, Egypt; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 21568, Alexandria, Egypt. Electronic address: asmaanour816@gmail.com., Hamida RS; Molecular Biology Unit, Department of Zoology, Faculty of Science, Alexandria University, Egypt., El-Dissouky A; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 21568, Alexandria, Egypt., Soliman HMA; Composites and Nano-Structured Materials Research Department, Advanced Technology and New Materials Research Institute, City of Scientific Research and Technological Applications, P.O. Box 21934, New Borg El-Arab, Alexandria, Egypt., Refaat HM; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 21568, Alexandria, Egypt.
Jazyk: angličtina
Zdroj: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2023 May; Vol. 225, pp. 113230. Date of Electronic Publication: 2023 Feb 28.
DOI: 10.1016/j.colsurfb.2023.113230
Abstrakt: Bismuth Telluride (Bi 2 Te 3 ) layered structure results in extraordinary features in diagnostic and therapeutic applications. However, Bi 2 Te 3 synthesis with reliable stability and biocompatibility in biological systems was the major challenge that limited its biological application. Herein, reduced graphene oxide (RGO) or graphitic carbon nitride (CN) nanosheets were incorporated into Bi 2 Te 3 matrix to improve exfoliation. Bi 2 Te 3 nanoparticles (NPs) and its novel nanocomposites (NCs): CN@Bi 2 Te 3 and CN-RGO@Bi 2 Te 3 were solvothermally synthesized, physiochemically characterized and assessed for their anticancer, antioxidant, and antibacterial activities. X-ray diffraction depicted Bi 2 Te 3 rhombohedral lattice structure. Fourier-transform infrared and Raman spectra confirmed NC formation. Scanning and transmission electron microscopy revealed 13 nm thickness and 400-600 nm diameter of hexagonal, binary, and ternary nanosheets of Bi 2 Te 3 -NPs/NCs. Energy dispersive X-ray Spectroscopy revealed the presence of Bi, Te, and carbon atoms in the tested NPs with negatively charged surfaces as depicted by zeta sizer. CN-RGO@Bi 2 Te 3 -NC displayed the smallest nanodiameter (359.7 nm) with the highest Brunauer-Emmett-Teller surface area and antiproliferative activity against MCF-7, HepG2 and Caco-2. Bi 2 Te 3 -NPs had the greatest scavenging activity (96.13 ± 0.4%) compared to the NCs. The NPs inhibitory activity was greater against Gram-negative bacteria than that of Gram-positive bacteria. Integration of RGO and CN with Bi 2 Te 3 -NPs enhanced their physicochemical properties and therapeutic activities giving rise to their promising capacity for future biomedical applications.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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