Efficacy of detergent-based cleaning and wiping against SARS-CoV-2 on high-touch surfaces.

Autor:	Nelson SW; Bioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA., Hardison RL; Bioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA., Limmer R; Battelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA., Marx J; Battelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA., Taylor BM; Battelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA., James RR; Bioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA., Stewart MJ; U.S. EPA, Office of Research and Development, Durham, NC 27711, USA., Lee SD; U.S. EPA, Office of Research and Development, Durham, NC 27711, USA., Calfee MW; U.S. EPA, Office of Research and Development, Durham, NC 27711, USA., Ryan SP; U.S. EPA, Office of Research and Development, Durham, NC 27711, USA., Howard MW; Bioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA.
Jazyk:	angličtina
Zdroj:	Letters in applied microbiology [Lett Appl Microbiol] 2023 Mar 01; Vol. 76 (3).
DOI:	10.1093/lambio/ovad033
Abstrakt:	Efficacy of cleaning methods against SARS-CoV-2 suspended in either 5% soil load (SARS-soil) or simulated saliva (SARS-SS) was evaluated immediately (hydrated virus, T0) or 2 hours post-contamination (dried virus, T2). Hard water dampened wiping (DW) of surfaces, resulted in 1.77-3.91 log reduction (T0) or 0.93-2.41 log reduction (T2). Incorporating surface pre-wetting by spraying with a detergent solution (D + DW) or hard water (W + DW) just prior to dampened wiping did not unilaterally increase efficacy against infectious SARS-CoV-2, however, the effect was nuanced with respect to surface, viral matrix, and time. Cleaning efficacy on porous surfaces (seat fabric, SF) was low. W + DW on stainless steel (SS) was as effective as D + DW for all conditions except SARS-soil at T2 on SS. DW was the only method that consistently resulted in > 3-log reduction of hydrated (T0) SARS-CoV-2 on SS and ABS plastic. These results suggest that wiping with a hard water dampened wipe can reduce infectious virus on hard non-porous surfaces. Pre-wetting surfaces with surfactants did not significantly increase efficacy for the conditions tested. Surface material, presence or absence of pre-wetting, and time post-contamination affect efficacy of cleaning methods. (Published by Oxford University Press on behalf of Applied Microbiology International 2023.)
Databáze:	MEDLINE
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