Does Gender Affect the Outcomes of Myocardial Revascularization for Left-Main Coronary Artery Disease?

Autor:	Daoulah A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Elsheikh-Mohamed NE; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Yousif N; Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Kingdom of Bahrain, Manama, Bahrain., Hersi AS; Department of Cardiac Sciences, King Fahad Cardiac Center, King Saud University, Riyadh, Saudi Arabia., Alharbi AW; Department of Internal Medicine, Gastroenterology Section, Gastroenterologist & Advanced Therapeutic Endoscopist, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Almahmeed W; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE., Alshehri M; Department of Cardiology, Armed Forces Hospitals Southern Region, Khamis Mushait, Saudi Arabia., Alzahrani B; Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia., Elfarnawany A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Alasmari A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Abuelatta R; Department of Cardiology, Madinah Cardiac Center, Madinah, Saudi Arabia., Al Garni T; Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia., Ghani MA; Department of Cardiology, Madinah Cardiac Center, Madinah, Saudi Arabia., Amin H; Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Kingdom of Bahrain, Manama, Bahrain., Hashmani S; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE., Al Nasser FOM; Department of Cardiology, Madinah Cardiac Center, Madinah, Saudi Arabia., Hiremath N; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE., Arafat AA; Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.; Department of Cardiothoracic Surgery, Tanta University, Tanta, Egypt., Elmahrouk Y; Tanta University, Tanta, Egypt., Kazim HM; Department of Cardiology, Alhada Armed Forces Hospital, Taif, Saudi Arabia., Refaat W; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Selim E; Department of Cardiology, Alhada Armed Forces Hospital, Taif, Saudi Arabia., Jamjoom A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., El-Sayed O; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Dahdouh Z; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Aithal J; Department of Cardiology, Yas Clinic Khalifa City, Abu Dhabi, UAE., Ibrahim AM; Department of Cardiology, Saudi German Hospital, Jeddah, Saudi Arabia., Elganady A; Department of Cardiology, Dr Erfan and Bagedo General Hospital, Jeddah, Saudi Arabia., Qutub MA; Cardiology Center of Excellence, Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alama MN; Cardiology Center of Excellence, Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Abohasan A; Department of Cardiology, Prince Sultan Cardiac Center in Qassim, Buraydah, Saudi Arabia., Hassan T; Department of Cardiology, Bugshan General Hospital, Jeddah, Saudi Arabia., Balghith M; King Abdulaziz Cardiac Center, College of Medicine, King Saud Bin Abdulaziz University for Health Science, Riyadh, Saudi Arabia., Hussien AF; Department of Cardiology, International Medical Center, Jeddah, Kingdom of Saudi Arabia., Abdulhabeeb IAM; Department of Cardiology, King Abdulaziz Specialist Hospital, Al Jawf, Saudi Arabia., Ahmad O; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Ramadan M; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Alqahtani AH; Department of Emergency Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Qenawi W; Department of Cardiology, Armed Forces Hospitals Southern Region, Khamis Mushait, Saudi Arabia., Shawky A; Department of Cardiology, Armed Forces Hospitals Southern Region, Khamis Mushait, Saudi Arabia., Ghonim AA; Department of Cardiology, Prince Sultan Cardiac Center Al Hassa, Hofuf, Saudi Arabia., Elmahrouk A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.; Department of Cardiothoracic Surgery, Tanta University, Tanta, Egypt., Naser MJ; Department of Internal Medicine, Baystate Medical Center, Springfield, MA, USA., Abozenah M; Department of Cardiovascular Medicine, University of Massachusetts Chan Medical School, Baystate Medical Center, Springfield, MA, USA., Shawky AM; Department of Cardiology, Dr Erfan and Bagedo General Hospital, Jeddah, Saudi Arabia., Alqahtani AM; Department of Cardiology, King Salman Heart Center, King Fahad Medical City, Riyadh, Saudi Arabia., Ahmed RA; Batterjee Medical College, Jeddah, Saudi Arabia., Abdelaziz AF; Department of Cardiothoracic and Vascular Surgery, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia., Alhamid S; Department of Emergency Medicine, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia., Lotfi A; Department of Cardiovascular Medicine, University of Massachusetts Chan Medical School, Baystate Medical Center, Springfield, MA, USA.
Jazyk:	angličtina
Zdroj:	Angiology [Angiology] 2024 Feb; Vol. 75 (2), pp. 182-189. Date of Electronic Publication: 2023 Mar 11.
DOI:	10.1177/00033197231162481
Abstrakt:	Currently, gender is not considered in the choice of the revascularization strategy for patients with unprotected left main coronary artery (ULMCA) disease. This study analyzed the effect of gender on the outcomes of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) in patients with ULMCA disease. Females who had PCI (n = 328) were compared with females who had CABG (n = 132) and PCI in males (n = 894) was compared with CABG (n = 784). Females with CABG had higher overall hospital mortality and major adverse cardiovascular events (MACE) than females with PCI. Male patients with CABG had higher MACE; however, mortality did not differ between males with CABG vs PCI. In female patients, follow-up mortality was significantly higher in CABG patients, and target lesion revascularization was higher in patients with PCI. Male patients had no difference in mortality and MACE between groups; however, MI was higher with CABG, and congestive heart failure was higher with PCI. In conclusion, women with ULMCA disease treated with PCI could have better survival with lower MACE compared with CABG. These differences were not evident in males treated with either CABG or PCI. PCI could be the preferred revascularization strategy in women with ULMCA disease. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu