| Autor: |
López-Pérez CA; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Santa Cruz-Pavlovich FJ; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Montiel-Cortés JE; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico.; Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Zapopan 44340, Mexico., Núñez-Muratalla A; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico.; Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico., Morán-González RB; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Villanueva-Gaona R; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Franco-Mojica X; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Moreno-Sandoval DG; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., González-Bañuelos JA; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., López-Pérez AU; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., Flores-González M; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico.; Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico., Grijalva-Ruiz C; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico.; Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico., Valdez-Mendoza ED; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico.; Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico., González-Lucano LR; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico., López-Zendejas M; Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico.; Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico. |
| Abstrakt: |
During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for in-hospital mortality of patients with COVID-19. A 2-year retrospective cohort study of hospitalized adult patients with COVID-19 pneumonia was conducted at a private tertiary care center. The study population consisted of 1258 patients with a median age of 56 ± 16.5 years, of whom 1093 recovered (86.8%) and 165 died (13.1%). In the univariate analysis, older age ( p < 0.001), comorbidities such as hypertension ( p < 0.001) and diabetes ( p < 0.001), signs and symptoms of respiratory distress, and markers of acute inflammatory response were significantly more frequent in non-survivors. The multivariate analysis showed that older age ( p < 0.001), the presence of cyanosis ( p = 0.005), and previous myocardial infarction ( p = 0.032) were independent predictors of mortality. In the studied cohort, the risk factors present at admission associated with increased mortality were older age, cyanosis, and a previous myocardial infarction, which can be used as valuable predictors for patients' outcomes. To our knowledge, this is the first study analyzing predictors of mortality in COVID-19 patients attended in a private tertiary hospital in Mexico. |
