Tear Film Dynamics between Low and High Contact Lens Dry Eye Disease Questionnaire (CLDEQ-8) Score with a Lehfilcon A Silicone Hydrogel Water Gradient Contact Lens: A Non-Invasive Methodology Approach.

Autor: Capote-Puente R; Department of Physics of Condensed Matter, Optica Area, Vision Research Group (CIVIUS), Faculty of Pharmacy, University of Seville, 41012 Seville, Spain., Bautista-Llamas MJ; Department of Physics of Condensed Matter, Optica Area, Vision Research Group (CIVIUS), Faculty of Pharmacy, University of Seville, 41012 Seville, Spain., Sánchez-González JM; Department of Physics of Condensed Matter, Optica Area, Vision Research Group (CIVIUS), Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2023 Mar 01; Vol. 13 (5). Date of Electronic Publication: 2023 Mar 01.
DOI: 10.3390/diagnostics13050939
Abstrakt: The purpose of this study is to evaluate the tear film dynamics between individuals with low and high Contact Lens Dry Eye Disease Questionnaire (CLDEQ-8) scores when wearing Lehfilcon A silicone hydrogel water gradient contact lenses. In this study, we implemented a longitudinal, single-location, self-comparison investigation. Variables measured included conjunctival redness, lipid layer thickness, tear meniscus height, first and mean non-invasive break-up time, CLDEQ-8, and standard patient evaluation of eye dryness (SPEED). In the second phase, participants were re-evaluated after 30 days of wearing the contact lenses to assess the tear film wearing the lenses. In a longitudinal comparison by group, we found that lipid layer thickness decreased 1.52 ± 1.38 ( p < 0.01) and 0.70 ± 1.30 ( p = 0.01) Guillon patterns degrees in the low and high CLDEQ-8 group, respectively. MNIBUT increased in 11.93 ± 17.93 ( p < 0.01) and 7.06 ± 12.07 ( p < 0.01) seconds. Finally, LOT increased in 22.19 ± 27.57 ( p < 0.01) and 16.87 ± 25.09 ( p < 0.01). In conclusion, this study demonstrates the effectiveness of Lehfilcon A silicone hydrogel water gradient contact lenses in improving tear film stability and reducing subjective dry eye symptoms in individuals with low and high CLDEQ-8 scores. However, it also led to an increase in conjunctival redness and a decrease in tear meniscus height.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje