Assessment of Blood Microcirculation Changes after COVID-19 Using Wearable Laser Doppler Flowmetry.

Autor: Zharkikh EV; Research and Development Center of Biomedical Photonics, Orel State University, Komsomolskaya 95, Orel 302026, Russia., Loktionova YI; Research and Development Center of Biomedical Photonics, Orel State University, Komsomolskaya 95, Orel 302026, Russia., Fedorovich AA; Research and Development Center of Biomedical Photonics, Orel State University, Komsomolskaya 95, Orel 302026, Russia.; National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of the Russian Federation, Petroverigsky 10, Moscow 101990, Russia., Gorshkov AY; National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of the Russian Federation, Petroverigsky 10, Moscow 101990, Russia., Dunaev AV; Research and Development Center of Biomedical Photonics, Orel State University, Komsomolskaya 95, Orel 302026, Russia.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2023 Mar 01; Vol. 13 (5). Date of Electronic Publication: 2023 Mar 01.
DOI: 10.3390/diagnostics13050920
Abstrakt: The present work is focused on the study of changes in microcirculation parameters in patients who have undergone COVID-19 by means of wearable laser Doppler flowmetry (LDF) devices. The microcirculatory system is known to play a key role in the pathogenesis of COVID-19, and its disorders manifest themselves long after the patient has recovered. In the present work, microcirculatory changes were studied in dynamics on one patient for 10 days before his disease and 26 days after his recovery, and data from the group of patients undergoing rehabilitation after COVID-19 were compared with the data from a control group. A system consisting of several wearable laser Doppler flowmetry analysers was used for the studies. The patients were found to have reduced cutaneous perfusion and changes in the amplitude-frequency pattern of the LDF signal. The obtained data confirm that microcirculatory bed dysfunction is present in patients for a long period after the recovery from COVID-19.
Databáze: MEDLINE
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