ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age.

Autor: Camacho-Moll ME; Department of Molecular Biology, Center for Biomedical Research at Northeast, Mexican Social Security Institute, Calle 2 de abril 501, Col. Independencia, Monterrey, Nuevo Leon, 64720, Mexico.; Center for Molecular Diagnosis and Personalized Medicine, Health Sciences Division, Universidad de Monterrey, Av. Ignacio Morones Prieto 4500-Pte, Zona Valle Poniente, Nuevo Leon, 66238, San Pedro Garza Garcia, Mexico., Ramírez-Daher Z; Residency in Geriatrics, Zone General Hospital No. 4, Mexican Social Security Institute, C. Mariano Matamoros 300, Centro de Guadalupe, Guadalupe, Nuevo Leon, 67100, Mexico., Escobedo-Guajardo BL; Department of Molecular Biology, Center for Biomedical Research at Northeast, Mexican Social Security Institute, Calle 2 de abril 501, Col. Independencia, Monterrey, Nuevo Leon, 64720, Mexico., Dávila-Valero JC; Residency in Geriatrics, Zone General Hospital No. 4, Mexican Social Security Institute, C. Mariano Matamoros 300, Centro de Guadalupe, Guadalupe, Nuevo Leon, 67100, Mexico., Rodríguez-de la Garza BL; Residency in Geriatrics, Zone General Hospital No. 4, Mexican Social Security Institute, C. Mariano Matamoros 300, Centro de Guadalupe, Guadalupe, Nuevo Leon, 67100, Mexico. brenda.rodriguezgar@imss.gob.mx., Bermúdez de León M; Department of Molecular Biology, Center for Biomedical Research at Northeast, Mexican Social Security Institute, Calle 2 de abril 501, Col. Independencia, Monterrey, Nuevo Leon, 64720, Mexico. mario.bermudez@imss.gob.mx.
Jazyk: angličtina
Zdroj: BMC geriatrics [BMC Geriatr] 2023 Mar 10; Vol. 23 (1), pp. 138. Date of Electronic Publication: 2023 Mar 10.
DOI: 10.1186/s12877-023-03864-8
Abstrakt: Background: One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with comorbidities, which are risk factors for severe COVID-19 infection. Among the tools that have been evaluated to predict intensive care unit (ICU) admission and mortality is ABC-GOALScl.
Aim: In the present study we validated the utility of ABC-GOALScl to predict in-hospital mortality in subjects over 60 years of age who were positive for SARS-CoV-2 virus at the moment of admission with the purpose of optimizing sanitary resources and offering personalized treatment for these patients.
Methods: This was an observational, descriptive, transversal, non-interventional and retrospective study of subjects (≥ 60 years of age), hospitalized due to COVID-19 infection at a general hospital in northeastern Mexico. A logistical regression model was used for data analysis.
Results: Two hundred forty-three subjects were included in the study, whom 145 (59.7%) passed away, while 98 (40.3%) were discharged. Average age was 71, and 57.6% were male. The prediction model ABC-GOALScl included sex, body mass index, Charlson comorbidity index, dyspnea, arterial pressure, respiratory frequency, SpFi coefficient (Saturation of oxygen/Fraction of inspired oxygen ratio), serum levels of glucose, albumin, and lactate dehydrogenase; all were measured at the moment of admission. The area under the curve for the scale with respect to the variable of discharge due to death was 0.73 (IC 95% = 0.662-0.792).
Conclusion: The ABC-GOALScl scale to predict ICU admission in COVID-19 patients is also useful to predict in-hospital death in COVID-19 patients  ≥ 60 years old.
(© 2023. The Author(s).)
Databáze: MEDLINE
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