Preoperative Serum Albumin Level Predicts Length of Stay and Perioperative Adverse Events Following Vertebral Corpectomy and Posterior Stabilization for Metastatic Spine Disease.

Autor:	Hirase T; Department of Orthopedic and Sports Medicine, Houston Methodist Hospital, Houston, TX, USA., Taghlabi KM; Department of Neurosurgery, Houston MethodistHospital, Houston, TX, USA., Cruz-Garza JG; Department of Neurosurgery, Houston MethodistHospital, Houston, TX, USA., Faraji AH; Department of Neurosurgery, Houston MethodistHospital, Houston, TX, USA., Marco RAW; Department of Orthopedic and Sports Medicine, Houston Methodist Hospital, Houston, TX, USA., Saifi C; Department of Orthopedic and Sports Medicine, Houston Methodist Hospital, Houston, TX, USA.
Jazyk:	angličtina
Zdroj:	Global spine journal [Global Spine J] 2024 Sep; Vol. 14 (7), pp. 2004-2011. Date of Electronic Publication: 2023 Mar 10.
DOI:	10.1177/21925682231163814
Abstrakt:	Study Design: Retrospective review of a prospectively collected national database. Objectives: To determine the association between preoperative serum albumin levels and perioperative adverse events (AEs) following vertebral corpectomy and posterior stabilization for metastatic spine disease. Methods: The 2010 to 2019 American College of Surgeons' National Surgical Quality Improvement (ACS-NSQIP) database was used to identify all patients undergoing vertebral corpectomy and posterior stabilization for metastatic spine disease. Receiver operative characteristic (ROC) curve analysis was used to determine preoperative serum albumin cut-off values for predicting perioperative AEs. Low preoperative serum albumin was defined as serum albumin below this cut-off value. Results: A total of 301 patients were included in the study. ROC curve analysis demonstrated serum albumin < 3.25 g/dL as a cut-off value for predicting perioperative AEs. The low serum albumin group had a higher overall perioperative AEs ( P = .041), longer post-operative LOS ( P < .001), higher 30-day reoperation rate ( P = .014), and a higher in-hospital mortality rate ( P = .046). Multivariate analysis demonstrated that low preoperative serum albumin was associated with higher perioperative AEs. Conclusions: Low serum albumin level is associated with higher perioperative AEs, longer postoperative LOS, and higher rates of 30-day reoperation and in-hospital mortality among patients undergoing vertebral corpectomy and posterior stabilization for metastatic spine disease. Strategies to improve preoperative nutritional status in patients undergoing this procedure may improve these perioperative outcome measures within this surgical population. Level of Evidence: III. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Takashi Hirase, Khaled Taghlabi, Jesus Cruz-Garza, and Amir Faraji has no conflicts of interests to disclose. Rex Marco has the following disclosures: DePuy, A Johnson & Johnson Company: Paid presenter or speaker Globus Medical: IP royalties. Comron Saifi has the following disclosures: Acquisition of Vertera Inc. by NuVasive’ Shares: Stock or stock Options. Alphatec Spine: Stock or stock Options. Nuvasive: Paid consultant. Restor3d: Stock or stock Options.
Databáze:	MEDLINE
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