Developmental trajectory of transmission speed in the human brain.

Autor: van Blooijs D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.; Stichting Epilepsie Instellingen Nederland (SEIN), Zwolle, the Netherlands., van den Boom MA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA., van der Aar JF; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Huiskamp GM; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Castegnaro G; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Demuru M; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Zweiphenning WJEM; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., van Eijsden P; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Miller KJ; Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA., Leijten FSS; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands., Hermes D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. hermes.dora@mayo.edu.
Jazyk: angličtina
Zdroj: Nature neuroscience [Nat Neurosci] 2023 Apr; Vol. 26 (4), pp. 537-541. Date of Electronic Publication: 2023 Mar 09.
DOI: 10.1038/s41593-023-01272-0
Abstrakt: The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.
(© 2023. The Author(s).)
Databáze: MEDLINE