Putting aging on ICE.
| Autor: | Teefy BB; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA., Benayoun BA; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA; Molecular and Computational Biology Department, USC Dornsife College of Letters, Arts and Sciences, Los Angeles, CA 90089, USA; Biochemistry and Molecular Medicine Department, USC Keck School of Medicine, Los Angeles, CA 90089, USA; USC Norris Comprehensive Cancer Center, Epigenetics and Gene Regulation, Los Angeles, CA 90089, USA; USC Stem Cell Initiative, Los Angeles, CA 90089, USA. Electronic address: berenice.benayoun@usc.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Cell metabolism [Cell Metab] 2023 Mar 07; Vol. 35 (3), pp. 383-385. |
| DOI: | 10.1016/j.cmet.2023.02.012 |
| Abstrakt: | A recent report by Yang et al. in Cell demonstrates that faithful DNA double-strand breaks and repair cycles phenocopy many aspects of aging in mice. Whether this progeroid phenotype is caused by a loss of epigenetic information remains to be conclusively determined. Competing Interests: Declaration of interests The authors have no conflicts of interest. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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