Bilateral Retinal Artery Occlusions and Uveitis as the First Manifestation of Crohn's Disease.

Autor:	Wu LA; Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Chu YC; Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Wang JK; Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.; Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.; Department of Electrical Engineering, Yuan Ze University, Taoyuan, Taiwan., Hsu YR; Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.; Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.; Department of Electrical Engineering, Yuan Ze University, Taoyuan, Taiwan.
Jazyk:	angličtina
Zdroj:	Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Jul; Vol. 32 (5), pp. 767-770. Date of Electronic Publication: 2023 Mar 08.
DOI:	10.1080/09273948.2023.2184700
Abstrakt:	Purpose: To present a case of newly diagnosed Crohn's disease, in which retinal artery occlusion (RAO) with uveitis was the first clinical manifestation. Case Description: A 55-year-old man presented with bilateral blurred vision, with decreased best corrected visual acuity (BCVA) to light perception (right eye, RE) and 20/40 (left eye, LE). Ophthalmological examination revealed bilateral iritis, vitritis, disc edema, and retinal vascular occlusions. Because of concurrent fever and leukocytosis, a systemic infection was highly suspected. However, whole-body imaging was unrevealing. Subsequently, the patient presented with massive bloody stool. Histopathological specimen from emergent hemicolectomy confirmed transmural granulomatous inflammation. Crohn's disease was finally diagnosed. Following treatment, the BCVA recovered to 20/40 (RE) and 20/22 (LE). The systemic condition remained stable after a 3-year follow-up. Conclusion: RAO with uveitis is a possible manifestation of Crohn's disease. In complex uveitis cases, clinicians should be aware of inflammatory bowel diseases as an important differential diagnosis.
Databáze:	MEDLINE
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