Efficiency analysis of commercial polymeric membranes for bone regeneration in rat cranial defects.

Autor:	Araújo LK; Universidade Federal do Ceará - Postgraduate Program in Biotechnology - Sobral (CE), Brazil., Lopes MS; Universidade Federal do Ceará - Dental School - Sobral (CE), Brazil., Souza FFP; Universidade Federal do Ceará - Postgraduate Program in Biotechnology of Natural Resources - Fortaleza (CE), Brazil., Melo MM; Universidade Federal do Ceará - Postgraduate Program in Biotechnology - Sobral (CE), Brazil., Paulo AO; Instituto de Educação Superior de Brasília - Dental School - Brasilia (DF), Brazil., Castro-Silva II; Universidade Federal do Ceará - Postgraduate Program in Biotechnology - Sobral (CE), Brazil.
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2023 Mar 06; Vol. 38, pp. e380623. Date of Electronic Publication: 2023 Mar 06 (Print Publication: 2023).
DOI:	10.1590/acb380623
Abstrakt:	Purpose: To evaluate the in vivo efficiency of commercial polymeric membranes for guided bone regeneration. Methods: Rat calvarial critical size defects was treated with LuminaCoat (LC), Surgitime PTFE (SP), GenDerm (GD), Pratix (PR), Techgraft (TG) or control (C-) and histomorphometric analysis determined the percentage of new bone, connective tissue and biomaterial at 1 or 3 months. Statistical analysis used ANOVA with Tukey's post-test for means at same experimental time and the paired Student's t test between the two periods, considering p < 0.05. Results: New bone at 1 month was higher for SP, TG and C-, at 3 months there were no differences, and between 1 and 3 months PR had greater increase growthing. Connective tissue at 1 month was higher for C-, at 3 months for PR, TG and C-, and between 1 and 3 months C- had sharp decline. Biomaterial at 1 month was higher for LC, in 3 months for SP and TG, and between 1 and 3 months, LC, GD and TG had more decreasing mean. Conclusions: SP had greater osteopromotive capacity and limitation of connective ingrowth, but did not exhibit degradation. PR and TG had favorable osteopromotion, LC less connective tissue and GD more accelerated biodegradation.
Databáze:	MEDLINE
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