| Autor: |
Nelson A; Department of Social and Psychological studies, Karlstad University, Karlstad, Sweden.; Department of Anaesthesiology, Central Hospital of Karlstad, Karlstad, Sweden., Malmberg Gavelin H; Department of Psychology, Umeå University, Umeå, Sweden., Andersson M; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden., Josefsson M; Centre for Demographic and Ageing Research (CEDAR), Umeå University, Umeå, Sweden.; Department of Statistics, USBE, Umeå University, Umeå, Sweden., Eskilsson T; Department of Public Health and Clinical Medicine, Section for Sustainable Health, Umeå University, Umeå, Sweden.; Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden., Slunga Järvholm L; Department of Public Health and Clinical Medicine, Section for Sustainable Health, Umeå University, Umeå, Sweden., Stigsdotter Neely A; Department of Social and Psychological studies, Karlstad University, Karlstad, Sweden.; Department of Social Sciences, Technology and Arts; Department of Health, Education and Technology, Luleå University of Technology, Luleå, Sweden., Boraxbekk CJ; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.; Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark.; Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.; Institute of Sports Medicine Copenhagen (ISMC) and Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark. |
| Abstrakt: |
Stress-related exhaustion is associated with cognitive deficits, measured subjectively using questionnaires targeting everyday slips and failures or more objectively as performance on cognitive tests. Yet, only weak associations between subjective and objective cognitive measures in this group has been presented, theorized to reflect recruitment of compensational resources during cognitive testing. This explorative study investigated how subjectively reported symptoms of cognitive functioning and burnout levels relate to performance as well as neural activation during a response inhibition task. To this end, 56 patients diagnosed with stress-related exhaustion disorder (ED; ICD-10 code F43.8A) completed functional magnetic resonance imaging (fMRI) using a Flanker paradigm. In order to investigate associations between neural activity and subjective cognitive complaints (SCCs) and burnout, respectively, scores on the Prospective and Retrospective Memory Questionnaire (PRMQ) and the Shirom-Melamed Burnout Questionnaire (SMBQ) were added as covariates of interest to a general linear model at the whole-brain level. In agreement with previous research, the results showed that SCCs and burnout levels were largely unrelated to task performance. Moreover, we did not see any correlations between these self-report measures and altered neural activity in frontal brain regions. Instead, we observed an association between the PRMQ and increased neural activity in an occipitally situated cluster. We propose that this finding may reflect compensational processes at the level of basic visual attention which could go unnoticed in cognitive testing but still be reflected in the experience of deficits in everyday cognitive functioning. |
