Post Radical Prostatectomy Erectile Dysfunction. A Single Centre Experience.

Autor:	Pikramenos K; Second Department of Urology, National and Kapodistrian University of Athens, Sismanoglio General Hospital, Athens, GRC., Zachou M; Gastroenterology, National and Kapodistrian University of Athens, Athens, GRC.; Gastroenterology, Sismanoglio General Hospital, Athens, GRC., Papadopoulos D; Anaesthesiology, Evgenidio Hospital, National and Kapodistrian University of Athens, Athens, GRC., Papatsoris A; Second Department of Urology, National and Kapodistrian University of Athens, Sismanoglio General Hospital, Athens, GRC., Varkarakis I; Second Department of Urology, National and Kapodistrian University of Athens, Sismanoglio General Hospital, Athens, GRC., Mitsogiannis I; Second Department of Urology, National and Kapodistrian University of Athens, Sismanoglio General Hospital, Athens, GRC.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Feb 03; Vol. 15 (2), pp. e34601. Date of Electronic Publication: 2023 Feb 03 (Print Publication: 2023).
DOI:	10.7759/cureus.34601
Abstrakt:	Introduction: This study aims to determine the effects of radical retropubic prostatectomy on post-operative erectile function. Materials & Methods: A total of 50 patients were included in this study, diagnosed with localized prostate cancer, and underwent nerve-sparing radical retropubic prostatectomy. All patients completed the International Index of Erectile Function (IIEF-5) questionnaire pre-operatively and on the third, sixth, and twelfth post-operative month and completed a self-reporting of their satisfaction with their sexual performance. Patients with a history of severe heart disease, were on erectile dysfunction medication, or had a score of 7 or less on the IIEF-5 questionnaire, were excluded from the study. Results: Pre-operatively it was observed that the lower the IIEF-5 score, the higher the biopsy Gleason score. Post-operatively, 16 patients stated that erectile function had returned to the pre-operative IIEF-5 category. In contrast, only 13 of them stated they were happy with their sexual performance on the self-reporting scale. The rest reported dissatisfaction despite returning to their pre-operative erectile function status. IIEF-5 scores were also different when compared amongst the four age groups, with scores indicating that younger age is related to higher IIEF-5 scores. At the 3-month follow-up, no statistically significant difference was observed between age groups. Finally, patients younger than 64 reported significantly less deterioration in post-operative erectile function. Conclusion: Post-radical prostatectomy erectile dysfunction remains one of the most pressing issues in prostate cancer therapy. A higher Gleason score has a more significant impact on pre-operative ED, and at the same time, the best post-operative ED results are observed in younger patients. Finally, patients need extensive follow-up, therapy, and pre-and post-operative psychological support to have the best possible erectile function. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Pikramenos et al.)
Databáze:	MEDLINE
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