Genome editing in maize: Toward improving complex traits in a global crop.

Autor:	Hernandes-Lopes J; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil., Yassitepe JECT; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil.; Embrapa Agricultura Digital, Campinas, SP, Brazil., Koltun A; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil., Pauwels L; Ghent University, Department of Plant Biotechnology and Bioinformatics, Ghent, Belgium.; VIB, Center for Plant Systems Biology, Ghent, Belgium., Silva VCHD; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil., Dante RA; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil.; Embrapa Agricultura Digital, Campinas, SP, Brazil., Gerhardt IR; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil.; Embrapa Agricultura Digital, Campinas, SP, Brazil., Arruda P; Universidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.; Universidade Estadual de Campinas, Centro de Biologia Molecular e Engenharia Genética, Campinas, SP, Brazil.; Universidade Estadual de Campinas, Instituto de Biologia, Departamento de Genética, Evolução, Microbiologia e Imunologia e Evolução, Campinas, SP, Brazil.
Jazyk:	angličtina
Zdroj:	Genetics and molecular biology [Genet Mol Biol] 2023 Mar 03; Vol. 46 (1 Suppl 1), pp. e20220217. Date of Electronic Publication: 2023 Mar 03 (Print Publication: 2023).
DOI:	10.1590/1678-4685-GMB-2022-0217
Abstrakt:	Recent advances in genome editing have enormously enhanced the effort to develop biotechnology crops for more sustainable food production. CRISPR/Cas, the most versatile genome-editing tool, has shown the potential to create genome modifications that range from gene knockout and gene expression pattern modulations to allele-specific changes in order to design superior genotypes harboring multiple improved agronomic traits. However, a frequent bottleneck is the delivery of CRISPR/Cas to crops that are less amenable to transformation and regeneration. Several technologies have recently been proposed to overcome transformation recalcitrance, including HI-Edit/IMGE and ectopic/transient expression of genes encoding morphogenic regulators. These technologies allow the eroding of the barriers that make crops inaccessible for genome editing. In this review, we discuss the advances in genome editing in crops with a particular focus on the use of technologies to improve complex traits such as water use efficiency, drought stress, and yield in maize.
Databáze:	MEDLINE
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