Cerebral Sinus Thrombosis and Immune Thrombocytopenia Post COVID-19 Vaccination: A Case Report and Narrative Review.

Autor: Ali A; Internal Medicine, Rosalind Franklin University of Medicine and Sciences, Chicago, USA., Dilibe A; Internal Medicine, East Carolina University Health, Greenville, USA., Rai S; Internal Medicine, Isra University, Hyderabad, PAK., Awosika A; College of Medicine, University of Illinois, Chicago, USA.; College of Health Sciences and Professions, Ohio University, Athens, USA., Omole AE; Anatomical Sciences, American University of Antigua, College of Medicine, Saint John, ATG., Ahmed M; Internal Medicine, Allied Hospital, Maple Heights, USA., Nwosu S; Hematology and Medical Oncology, Emory University, Atlanta, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Feb 02; Vol. 15 (2), pp. e34550. Date of Electronic Publication: 2023 Feb 02 (Print Publication: 2023).
DOI: 10.7759/cureus.34550
Abstrakt: Vaccine-induced immune thrombocytopenia and thrombosis (VITT) following the adenoviral vector COVID-19 vaccine is a rare adverse event. Although the risk of VITT following the COVID-19 vaccine appears to be low, early diagnosis and management can be lifesaving. We present a case of VITT in a young female who presented with persistent headaches and fevers followed by anisocoria and right-sided hemiplegia. Initial imaging was unremarkable, and labs showed thrombocytopenia and elevated d-dimers. Repeat imaging revealed thrombosis in the left transverse and superior sagittal sinuses, and she was diagnosed with VITT. She received combined treatment with intravenous immunoglobulins and systemic anticoagulation, resulting in an increased platelet count and resolution of her neurological symptoms.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Ali et al.)
Databáze: MEDLINE