Changes in medication regimen complexity index following medication-related hospital admissions: A retrospective single-centre study.
Autor: | Gillooly I; The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, Australia., Tan EC; The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, Australia., Wojt IR; The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, Australia., Patanwala AE; The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, Australia; Department of Pharmacy, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia., Cairns R; The University of Sydney, Faculty of Medicine and Health, School of Pharmacy, Sydney, Australia; New South Wales Poisons Information Centre, The Children's Hospital at Westmead, Sydney, Australia. Electronic address: rose.cairns@sydney.edu.au. |
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Jazyk: | angličtina |
Zdroj: | Research in social & administrative pharmacy : RSAP [Res Social Adm Pharm] 2023 Jun; Vol. 19 (6), pp. 969-972. Date of Electronic Publication: 2023 Feb 20. |
DOI: | 10.1016/j.sapharm.2023.02.011 |
Abstrakt: | Background: Medication-related hospitalisations present an opportunity for de-prescribing and simplification of medication regimens. The Medication Regimen Complexity Index (MRCI) is a tool for measuring the complexity of medication regimens. Objectives: To evaluate whether MRCI changes following medication-related hospitalisations, and to evaluate the relationship between MRCI, length of stay (LOS) in hospital, and patient characteristics. Methods: A retrospective medical record review of patients admitted to a tertiary referral hospital in Australia for medication-related problems, January 2019 to August 2020. MRCI was calculated using pre-admission medication lists and discharge medication lists. Results: There were 125 patients who met inclusion criteria. The median (IQR) age was 64.0 years (45.0-75.0) and 46.4% were female. Median MRCI decreased by 2.0 following hospitalisation: from median (IQR) 17.0 (7.0-34.5) on admission vs 15.0 (3.0-29.0) on discharge (p < 0.001). Admission MRCI predicted LOS ≥2 days (OR 1.03, 95%CI 1.00-1.05, p = 0.022). Allergic reaction-related hospitalisations were associated with lower admission MRCI. Conclusions: There was a decrease in MRCI following medication-related hospitalisation. Targeted medication reviews for high-risk patients (e.g., those with medication-related hospitalisations) could further reduce the burden of medication complexity following discharge from hospital and possibly prevent readmissions. (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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