The results of thrombectomy from the arteries of the lower extremities in patients infected with SARS-CoV-2 Omicron variant with different severity of respiratory failure.

Autor:	Kazantsev AN; Kostroma Regional Clinical Hospital named after E. I. Korolev, Kostroma, Russian Federation., Zharova AS; North-Western State Medical University named after I. I. Mechnikov, Saint Petersburg, Russian Federation., Shmatov DV; Clinic of High Medical Technologies named after N. I. Pirogov St Petersburg State University, Saint Petersburg, Russian Federation., Zakeryaev AB; Research Institute Regional Clinical Hospital No. 1 named. prof. S.V. Ochapovsky, Krasnodar, Russian Federation., Lider RY; Kemerovo State Medical University of the Ministry of Health of the Russian Federation, Kemerovo, Russian Federation., Kazantseva EG; Kemerovo State Medical University of the Ministry of Health of the Russian Federation, Kemerovo, Russian Federation., Bagdavadze GS; North-Western State Medical University named after I. I. Mechnikov, Saint Petersburg, Russian Federation., Korotkikh AV; Clinic of Cardiac Surgery of the Amur State Medical Academy of the Ministry of Health of Russia, Blagoveshchensk, Russian Federation., Lutsenko VA; Kemerovo Regional Clinical Hospital named after S. V. Belyaeva, Kemerovo, Russian Federation., Sultanov RV; Kemerovo Regional Clinical Hospital named after S. V. Belyaeva, Kemerovo, Russian Federation., Lebedev OV; Kostroma Regional Clinical Hospital named after E. I. Korolev, Kostroma, Russian Federation., Sirotkin AA; Kostroma Regional Clinical Hospital named after E. I. Korolev, Kostroma, Russian Federation., Snopova EV; Kostroma Regional Clinical Hospital named after E. I. Korolev, Kostroma, Russian Federation., Palagin PD; Kostroma Regional Clinical Hospital named after E. I. Korolev, Kostroma, Russian Federation.
Jazyk:	angličtina
Zdroj:	Vascular [Vascular] 2024 Aug; Vol. 32 (4), pp. 811-819. Date of Electronic Publication: 2023 Mar 03.
DOI:	10.1177/17085381231160933
Abstrakt:	Goal: Analysis of the results of thrombectomy from the arteries of the lower extremities in patients with COVID-19 against the background of different severity of respiratory failure. Materials and Methods: This retrospective, cohort, comparative study for the period from 05/01/2022 to 20/07/2022 included 305 patients with acute thrombosis of the arteries of the lower extremities against the background of the course of COVID-19 (SARS-CoV-2 Omicron variant). Depending on the type of oxygen support, 3 groups of patients were formed: group 1 ( n = 168) - oxygen insufflation through nasal cannulas; group 2 ( n = 92) - non-invasive lung ventilation; and group 3 ( n = 45) - artificial lung ventilation. Results: Myocardial infarction and ischemic stroke were not detected in the total sample. The highest number of deaths (group 1: 5.3%, n = 9; group 2: 72.8%, n = 67; group 3: 100%, n = 45; p < 0.0001), rethrombosis (group 1 : 18.4%, n = 31; group 2: 69.5%, n = 64; group 3: 91.1%, n = 41; p < 0.0001), and limb amputations (group 1: 9.5%, n = 16; group 2: 56.5%, n = 52; group 3: 91.1%, n = 41; p < 0.0001) was recorded in group 3 (ventilated) patients. Conclusion: In patients infected with COVID-19 and on artificial lung ventilation, a more aggressive course of the disease is noted, expressed in an increase in laboratory parameters (C-reactive protein, ferritin, interleukin-6, and D-dimer) of the degree of pneumonia (CT-4 in overwhelming number) and localization of thrombosis of the arteries of the lower extremities, mainly in the tibial arteries. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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