Epidemiology of Common Ocular Manifestations among Patients on Haemodialysis in West Bank, Palestine.

Autor: Shanti Y; Department of Opthalmology, An-Najah National University Hospital, Nablus, Palestine., Hamayel H; Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine., Yasin A; Department of Opthalmology, An-Najah National University Hospital, Nablus, Palestine., Shanab AA; Department of Opthalmology, An-Najah National University Hospital, Nablus, Palestine., Hroub O; Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine., Hamdan Z; Department of Nephrology, An-Najah National University Hospital, Nablus, Palestine., Shraim M; Department of Public Health, College of Health Sciences, Qatar University, QU Health, Doha, Qatar.
Jazyk: angličtina
Zdroj: Sultan Qaboos University medical journal [Sultan Qaboos Univ Med J] 2023 Feb; Vol. 23 (1), pp. 61-67. Date of Electronic Publication: 2023 Feb 23.
DOI: 10.18295/squmj.4.2022.032
Abstrakt: Objectives: This study aimed to assess the prevalence of ocular manifestations and associated factors in patients on haemodialysis.
Methods: A cross-sectional study of patients on haemodialysis from a haemodialysis unit in Nablus, Palestine, was conducted. Medical examination for ocular manifestations (intraocular pressure, cataract, retinal changes and optic neuropathy) was performed using Tono-Pen, portable slit-lamp and indirect ophthalmoscope. Predictor variables were age, gender, smoking, medical comorbidities (diabetes, hypertension, ischaemic heart disease [IHD], peripheral arterial disease [PAD]) and use of antiplatelet or anti-coagulation medications.
Results: A total of 191 patients were included in this study. The prevalence of any ocular manifestation in at least one eye was 68%. The most common ocular manifestations were retinal changes (58%) and cataract (41%). The prevalence of non-proliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR) and NPDR or PDR was 51%, 16% and 65%. Two patients had PDR in one eye and NPDR in the other, and therefore, they were counted only once making the total for this category 71 rather than 73 patients. An increase in age by one year increased the odds of having cataract by 1.10 (95% confidence interval [CI] = 1.06-1.14). Patients with diabetes had higher odds of having cataract (odds ratio [OR] = 7.43, 95% CI: 3.26-16.95) and any retinal changes (OR = 109.48, 95% CI: 33.85-354.05) than patients without diabetes. Patients with diabetes and IHD or PAD had higher odds of having NPDR than those with diabetes without IHD or PAD (OR = 7.62, 95% CI: 2.07-28.03).
Conclusion: Retinal changes and cataract are common ocular manifestations among patients on haemodialysis. The findings emphasise the importance of periodic screening for ocular problems in this vulnerable population, especially older patients and those with diabetes, to prevent visual impartment and associated disability.
Competing Interests: CONFLICTS OF INTEREST The authors declare no conflicts of interest.
(© Copyright 2023, Sultan Qaboos University Medical Journal, All Rights Reserved.)
Databáze: MEDLINE
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