Autor: |
Kouhpanji MRZ; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Zhang Y; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Um J; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Srinivasan K; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Sharma A; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Shore D; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455 USA., Gao Z; Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Chen Y; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455 USA., Harpel A; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455 USA., Porshokouh ZN; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Gage TE; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455 USA., Dragos-Pinzaru O; National Institute of Research and Development for Technical Physics, 700050 Iasi, Romania., Tabakovic I; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Visscher PB; Department of Physics and Astronomy, The University of Alabama, Tuscaloosa, AL 35401 USA., Bischof J; Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Modiano JF; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Falcon Heights, MN 55108 USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455 USA., Franklin R; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA., Stadler BJH; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455 USA.; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455 USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455 USA. |
Abstrakt: |
Magnetic nanowires (MNWs) can have their moments reversed via several mechanisms that are controlled using the composition, length, diameter, and density of nanowires in arrays as-synthesized or as individual nanoparticles in assays or gels. This tailoring of magnetic reversal leads to unique properties that can be used as a signature for reading out the type of MNW for applications as nano-barcodes. When synthesized inside track-etched polycarbonate membranes, the resulting MNW-embedded membranes can be used as biocompatible bandaids for detection without contact or optical sighting. When etched out of the growth template, free-floating MNWs are internalized by cells at 37 °C such that cells and/or exosomes can be collected and detected. In applications of cryopreservation, MNWs can be suspended in cryopreservation agents (CPAs) for injection into the blood vessels of tissues and organs as they are vitrified to -200 °C. Using an alternating magnetic field, the MNWs can then be nanowarmed rapidly to prevent crystallization and uniformly to prevent cracking of specimens, for example, as grafts or transplants. This invited paper is a review of recent progress in the specific bioapplications of MNWs to barcodes, biocomposites, and nanowarmers. |