Vascular density and macular sensitivity in eyes after scleral buckling surgery for macula-on rhegmatogenous retinal detachment.

Autor: Zabel P; Department of Sensory Organ Studies, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.; Oftalmika Eye Hospital, Bydgoszcz, Poland., Zabel K; Department of Sensory Organ Studies, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.; Oftalmika Eye Hospital, Bydgoszcz, Poland., Kazmierczak K; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Stankiewicz M; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Jaworski D; Division of Ophthalmology and Optometry, Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Suwala K; Department of Sensory Organ Studies, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Buszko K; Department of Biostatistics and Biomedical Systems Theory, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Stafiej J; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Malukiewicz G; Department of Ophthalmology, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland., Kaluzny JJ; Department of Sensory Organ Studies, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.; Oftalmika Eye Hospital, Bydgoszcz, Poland.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Mar 02; Vol. 18 (3), pp. e0279683. Date of Electronic Publication: 2023 Mar 02 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0279683
Abstrakt: Purpose: To investigate the structure and function of the retina after scleral buckling (SB) surgery due to macula-on rhegmatogenous retinal detachment (RRD).
Methods: Twenty eyes with repaired macula-on RRD and 20 fellow eyes were included. All patients within 6-12 months of the procedure, were examined to evaluate retinal structure using spectral domain optical coherence tomography (SD-OCT) and vessel density (VD) by OCT angiography (OCTA). Best corrected visual acuity (BCVA) and microperimetry (MP) tests were used to assess retinal function.
Results: Analysis of the microvascular network using OCTA between the operated and healthy fellow eyes showed a significant reduction on VD in superficial vascular plexus (SVP), deep vascular plexus (DVP) and radial peripapillary capillaries (RPC) (p< 0.001, p = 0.019 and p = 0.008, respectively). Comparison of retinal structure in SD-OCT showed no significant differences on thickness in ganglion cell complex (GCC) and peripaillary retinal nerve fiber layer (pRNFL) (p> 0.05) between examined eyes. Retinal function analysis by MP examination showed a decrease of retinal sensitivity (p = 0.0013) whereas postoperative BCVA showed no differences (p = 0.62) in the operated eyes. Significant Pearson's correlations were observed between retinal sensitivity and VD in SVP, RPC (p< 0.05).
Conclusion: In the eyes after SB surgery due to macula-on RRD, changes in retinal sensitivity were accompanied by impairment of the microvascular network assessed by the OCTA.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Zabel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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