Trends in human leptospirosis in Denmark, 2012-2021.

Autor:	Eves C; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Kjelsø C; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Benedetti G; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Jørgensen CS; Department of Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Krogfelt KA; Department of Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.; Department of Science and Environment, PandemiX Center, Roskilde University, Roskilde, Denmark.
Jazyk:	angličtina
Zdroj:	Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Feb 13; Vol. 13, pp. 1079946. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
DOI:	10.3389/fcimb.2023.1079946
Abstrakt:	Leptospirosis is a zoonotic bacterial infection that can cause influenza-like symptoms and severe disease. In Denmark, leptospirosis is rare, non-endemic, and most commonly transferred to humans from mice and rats. Cases of human leptospirosis in Denmark are by law notifiable to Statens Serum Institut. This study aimed to describe trends in incidence of leptospirosis in Denmark from 2012 to 2021. Descriptive analyses were used to calculate the incidence, geographical distribution and possible routes of infection, as well as testing capacity and serological trends. The overall incidence rate was 0.23 per 100,000 inhabitants, with the highest annual incidence of 24 cases in 2017. Men between 40-49 years old were the demographic group most commonly diagnosed with leptospirosis. August and September were the months with highest incidence over the entire study period. The most common serovar observed was Icterohaemorrhagiae, although over a third of cases were diagnosed via polymerase chain reaction alone. The most common sources of exposure reported were travel abroad, farming, and recreational contact with fresh water, the latter being a new exposure compared to previous studies. Overall, a One Health approach would ensure better detection of outbreaks and milder disease. Additionally, preventative measures should be expanded to include recreational water sports. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Eves, Kjelsø, Benedetti, Jørgensen and Krogfelt.)
Databáze:	MEDLINE
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