Short and long-term oncologic outcomes of patients with colon cancer of the splenic flexure.

Autor: Zhang C; Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery Mayo Clinic Rochester, MN, USA., Calderon E; Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA., Chang YH; Department of Quantitative Health Sciences, Scottsdale, AZ, USA., Han GR; Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA., Kelley SR; Division of Colon and Rectal Surgery, Mayo Clinic Rochester, Rochester, MN, USA., Merchea A; Department of Colon and Rectal Surgery, Mayo Clinic Florida Jacksonville, FL, USA., Brady JT; Department of Colon and Rectal Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA., Young-Fadok TM; Department of Colon and Rectal Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA., Etzioni DA; Department of Colon and Rectal Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA., Mishra N; Department of Colon and Rectal Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA. Electronic address: mishra.nitin@mayo.edu.
Jazyk: angličtina
Zdroj: American journal of surgery [Am J Surg] 2023 Jul; Vol. 226 (1), pp. 77-82. Date of Electronic Publication: 2023 Feb 07.
DOI: 10.1016/j.amjsurg.2023.02.005
Abstrakt: Background: There is currently no consensus on surgical management of splenic flexure adenocarcinoma (SFA).
Methods: Patients undergoing surgical resection for SFA between 1993 and 2015 were identified. Postoperative outcomes were compared between patients who underwent segmental (SR) vs. anatomical resection (AR).
Results: One-hundred and thirteen patients underwent SR and 89 underwent AR. More patients in the SR group had open resections, but there were otherwise no differences in demographics or surgical characteristics between the two groups. There were no differences in overall (p = 0.29) or recurrence-free(p = 0.37) survival. On multivariable analysis, increased age (HR 1.04, 1.01-1.07, p = 0.005), higher American Society of Anesthesiology classification (HR 3.1, 1.7-5.71, p < 0.001), and higher tumor stage (HR 8.84, 3.76-20.82, p < 0.001) were predictive of mortality.
Conclusions: Short and long-term outcomes after SR and AR for SFA are not different, making SR a viable option for SFA surgical management.
Competing Interests: Declaration of competing interest The authors have no conflicts of interest to disclose.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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