Transcatheter Intervention for Coarctation of the Aorta: A Nordic Population-Based Registry With Long-Term Follow-Up.

Autor: Eriksson P; University of Gothenburg, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden. Electronic address: peter.eriksson@vgregion.se., Pihkala J; Helsinki University Hospital, University of Helsinki, Helsinki, Finland; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart (http://guardheart.ern-net.eu)., Jensen AS; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart (http://guardheart.ern-net.eu); Rigshospitalet-Copenhagen University Hospital, Copenhagen, Denmark., Dohlen G; Oslo University Hospital Rikshospitalet, Oslo, Norway., Liuba P; Skane University Hospital, Lund, Sweden., Wahlander H; University of Gothenburg, Institute of Clinical Science, Sahlgrenska Academy, Gothenburg, Sweden., Sjoberg G; Astrid Lindgren Children's Hospital and Department of Children's and Women's Health, Karolinska Institutet, Stockholm, Sweden., Hlebowicz J; Skane University Hospital, Lund, Sweden., Furenas E; University of Gothenburg, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden., Leirgul E; Haukeland University Hospital, Bergen, Norway., Settergren M; Department of Cardiology, Karolinska University Hospital and Division of Cardiology, Department of Medicine, Karolinska Institute, Stockholm, Sweden., Vithessonthi K; Oslo University Hospital Rikshospitalet, Oslo, Norway., Nielsen NE; Linköping University Hospital, Linköping, Sweden., Christersson C; Department of Medical Sciences, Uppsala University, Sweden., Sondergaard L; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart (http://guardheart.ern-net.eu); Rigshospitalet-Copenhagen University Hospital, Copenhagen, Denmark., Sinisalo J; Helsinki University Hospital, University of Helsinki, Helsinki, Finland; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart (http://guardheart.ern-net.eu)., Nielsen-Kudsk JE; Aarhus University Hospital, Aarhus, Denmark., Dellborg M; University of Gothenburg, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden., Larsen SH; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart (http://guardheart.ern-net.eu); Rigshospitalet-Copenhagen University Hospital, Copenhagen, Denmark; Aarhus University Hospital, Aarhus, Denmark.
Jazyk: angličtina
Zdroj: JACC. Cardiovascular interventions [JACC Cardiovasc Interv] 2023 Feb 27; Vol. 16 (4), pp. 444-453.
DOI: 10.1016/j.jcin.2022.11.007
Abstrakt: Background: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery.
Objectives: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years.
Methods: During the study period, 683 interventions were performed on 542 patients.
Results: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up.
Conclusions: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.
Competing Interests: Funding Support and Author Disclosures This work was funded by the Swedish state under the ALF agreement (grant 236611) and the Swedish Heart-Lung Foundation (grant 20180644) and Forskningsstiftelsen vid kardiologiska sektionen SU/Ostra Hospital. This study received no financial or other industry support. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
(Copyright © 2023 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE