Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection.

Autor: O'Toole RF; Department of Biomedicine and Medical Diagnostics, School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand. Electronic address: ronan.o'toole@aut.ac.nz., Leong KWC; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Victoria, Australia., Cumming V; Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Victoria, Australia., Van Hal SJ; Department of Infectious Disease and Microbiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Jazyk: angličtina
Zdroj: Research in microbiology [Res Microbiol] 2023 May; Vol. 174 (4), pp. 104046. Date of Electronic Publication: 2023 Feb 27.
DOI: 10.1016/j.resmic.2023.104046
Abstrakt: Enterococcus faecium is a major species in infections by vancomycin-resistant enterococci (VRE). New variants of the pathogen have emerged and become dominant in healthcare settings. Two such examples, vanB ST796 and vanA ST1421 sequence types, originally arose in Australia and proceeded to cause VRE outbreaks in other countries. Of concern is the detection in Europe of vancomycin variable enterococci (VVE) belonging to ST1421 that exhibit a vancomycin-susceptible phenotype but can revert to resistant in the presence of vancomycin. The recent application of genome sequencing for increasing our understanding of the evolution and spread of VRE is also explored here.
Competing Interests: Declaration of competing interest There is no conflict of interest.
(Copyright © 2023 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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