Assessing knowledge of sickle cell disease and health beliefs on premarital genetic screening among healthcare trainees at a tertiary institution: A cross-sectional study.

Autor: Agbozo WK; Department of Physician Assistantship Central University Miotso Ghana.; West African Genetic Medicine Centre (WAGMC) University of Ghana Legon-Accra Ghana., Amanor E; Department of Biochemistry and Biotechnology, College of Science Kwame Nkrumah University of Science and Technology Kumasi Ghana., Acheampong EO; Department of Epidemiology and Biostatistics Kwame Nkrumah University of Science and Technology Kumasi Ghana., Kotei B; Department of Nursing Central University Miotso Ghana., Attoh LN; Department of Nursing Central University Miotso Ghana., Yeboah D; Department of Physician Assistantship Central University Miotso Ghana., Odonkor P; Department of Physician Assistantship Central University Miotso Ghana., Obiri S; Department of Physician Assistantship Central University Miotso Ghana., Kwarteng A; Department of Biochemistry and Biotechnology, College of Science Kwame Nkrumah University of Science and Technology Kumasi Ghana.; Kumasi Centre for Collaborative Research in Tropical Medicine Kwame Nkrumah University of Science and Technology Kumasi Ghana., Larbi A; Department of Biochemistry and Biotechnology, College of Science Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Jazyk: angličtina
Zdroj: Health science reports [Health Sci Rep] 2023 Feb 24; Vol. 6 (2), pp. e1128. Date of Electronic Publication: 2023 Feb 24 (Print Publication: 2023).
DOI: 10.1002/hsr2.1128
Abstrakt: Background: The uptake of sickle cell trait (SCT) test is challenged by several factors. A community of healthcare professionals educating the public to undergo screening is critical in reducing the disease burden. We investigated knowledge and attitude towards premarital SCT screening among healthcare trainee students who are the next generation of healthcare practitioners.
Methods: A cross-sectional design was employed, and quantitative data were collected from 451 female students pursuing healthcare programs at a tertiary institution in Ghana. Descriptive, bivariate, and multivariate logistic regression analysis was performed.
Results: More than half of the participants were 20-24 years (54.55%) and had good knowledge (71.18%) about sickle cell disease (SCD). Age and school or social media as sources of information were significantly associated with good knowledge about SCD. Students between the age 20-24 (adjusted odds ratio [AOR] = 2.54, confidence interval [CI] = 1.30-4.97) and knowledge (AOR = 2.19, CI = 1.41-3.39) were 3 times and 2 times more likely to have a positive perception about SCD severity. Students who have SCT (AOR = 5.16, CI = 2.46-10.82), whose source of information was family member/friends (AOR = 2.83, CI = 1.44-5.59) and social media (AOR = 4.59, CI = 2.09-10.12) were 5 times, 2 times and 5 times likely to have a positive perception about the susceptibility of SCD. Students whose source of information is school (AOR = 2.06, CI = 1.11-3.81) and who have good knowledge of SCD (AOR = 2.25, CI = 1.44-3.52) were 2 times more likely to have a positive perception about the benefits of testing. Students with SCT (AOR = 2.64, CI = 1.36-5.13) and source of information was social media (AOR = 3.01, CI = 1.36-6.64) were about 3 times more likely to have a positive perception about the barriers to testing.
Conclusion: Our data shows that high level of SCD knowledge influences positive perceptions about the severity of SCD, the benefits and relatively low barriers to SCT or SCD testing and genetic counseling. Dissemination of SCT, SCD and premarital genetic counseling education should be intensified especially in schools.
Competing Interests: The authors declare no conflicts of interest.
(© 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz: