Acute severe thrombocytopenia following iodinated radiographic contrast medium infusion: a case report.

Autor: Sharawi BMM; Departments of Internal Medicine., Bashir BM; Oncology., Al-Tell A; Oncology., Hamdan M; Oncology., Abulihya MW; Pathology., Karama AJ; Hematology, Istishari Arab Hospital, Ramallah, Palestine.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Feb 06; Vol. 85 (2), pp. 187-190. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).
DOI: 10.1097/MS9.0000000000000150
Abstrakt: Acute contrast-induced thrombocytopenia is an unusual complication, and it is a rare event with the use of modern low-osmolarity iodinated contrast medium. There are only a few reports that exist in English literature.
Case Presentation: The authors report the case of a 79-year-old male patient with severe, life-threatening thrombocytopenia after administration of intravenous nonionic low-osmolarity contrast medium. His platelet count dropped from 179×10 9 /l to 2×10 9 /l after 1 h of radiocontrast infusion. Which has returned gradually to normal level within days with corticosteroid administration and platelet transfusion.
Conclusion: Iodinated contrast-induced thrombocytopenia is a rare complication with an unknown causative mechanism. There is no definitive treatment for this condition, with corticosteroids being used in most cases. The platelet count normalizes within a few days regardless of any interventions, but supportive treatment is important to avoid any unwanted complications. Further studies are still needed for a better understanding of the exact mechanism of this condition.
Competing Interests: The authors declare that they have no competing interests.
(© 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE