Pulmonary hypertension among patients hospitalized with acute heart failure in Buea, South West Region of Cameroon.
| Autor: | Nkoke C; Faculty of Health Sciences, University of Buea, Buea, Cameroon.; Clinical Research Education, Networking and Consultancy, Douala, Cameroon., Jingi AM; Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon., Noubiap JJ; Centre for Heart Rhythm disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia., Dzudie A; Clinical Research Education, Networking and Consultancy, Douala, Cameroon.; Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon. |
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| Jazyk: | angličtina |
| Zdroj: | The Pan African medical journal [Pan Afr Med J] 2022 Jul 20; Vol. 42, pp. 216. Date of Electronic Publication: 2022 Jul 20 (Print Publication: 2022). |
| DOI: | 10.11604/pamj.2022.42.216.33076 |
| Abstrakt: | Introduction: pulmonary hypertension (PH) is a common and severe complication in patients with heart failure (HF). It is associated with increased morbidity and mortality. There is limited data in Cameroon on the prevalence of PH in hospitalized HF patients and its impact on outcome. Methods: we analyzed data from consecutive adult patients hospitalized with. Pulmonary hypertension (PH) was defined as pulmonary artery systolic pressure (PASP) ≥ 35mmHg. Results: eighty-six (86) consecutive patients were hospitalized and 66(76.7%) had measurable PASP on echocardiography. Of those with echocardiographically measurable PASP (66), there were 39 (59.1%) females. The median (IQR) age was 60 (42-76) years. The prevalence of PH was 93.9%. PH was present in all (100%) patients with right heart failure (RHF) and in 62 (93.9%) patients with left heart failure (LHF). Severe PH (PASP ≥55 mmHg) was seen in 45 (68.2%, [95% CI: 55.6-75.1]) patients. The mean PASP was significantly higher in those with isolated RHF compared with those who had isolated left or bi-ventricular failure. Factors likely associated with moderate-to-severe PH (PASP ≥ 45 mmHg) were female sex, RHF, and right atrial dilatation. After adjusting for sex, right atrial dilation was independently associated with moderate-to-severe PH. In-hospital death occurred in 7 (10.6%, [95% CI: 4.4-20.6]) patients. The median (IQR) time to death was 6 (3-7) days and ranged from 2 to 8 days. All deaths (100%) occurred in those with moderate-to-severe PH. Conclusion: the prevalence of pulmonary hypertension in hospitalized heart failure patients was high with two third of the patients having severe PH, and most commonly occurred in females. All deaths occurred in patients with moderate-to-severe PH. Competing Interests: The authors declare no competing interests. (Copyright: Clovis Nkoke et al.) |
| Databáze: | MEDLINE |
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