Vasovagal Syncope and Pulseless Electrical Activity Cardiac Arrest in Patients With Immunoglobulin Light Chain Cardiac Amyloidosis: A Case Series.
Autor: | Sperry BW; Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, USA., Harhash AA; Department of Cardiology, University of Vermont, Burlington, USA., Cossor F; Department of Hematology, Saint Luke's Hospital, Kansas City, USA., Raza S; Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, USA. |
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Jazyk: | angličtina |
Zdroj: | Cureus [Cureus] 2023 Jan 23; Vol. 15 (1), pp. e34107. Date of Electronic Publication: 2023 Jan 23 (Print Publication: 2023). |
DOI: | 10.7759/cureus.34107 |
Abstrakt: | Immunoglobulin light chain (AL) amyloidosis may lead to amyloid fibril deposition into peripheral and autonomic nerves, resulting in resting and orthostatic hypotension. While most patients die from progressive heart failure, the most commonly proposed cardiac rhythm associated with sudden death is pulseless electrical activity (PEA). Herein, we describe four patients with severe AL cardiac amyloidosis who had witnessed cardiac arrest with pulseless electrical activity as a result of vasovagal syncope. Healthcare providers should be aware of severe autonomic dysfunction in cardiac amyloidosis and the potential for an abnormal vasovagal response leading to syncope or death. Competing Interests: The authors have declared financial relationships, which are detailed in the next section. (Copyright © 2023, Sperry et al.) |
Databáze: | MEDLINE |
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