Traditionally used medicinal plants mediate the biosynthesis of silver nanoparticles: methodological, larvicidal, and ecotoxicological approach.

Autor: Kamaraj C; Interdisciplinary Institute of Indian System of Medicine (IIISM), Directorate of Research, SRM Institute of Science and Technology (SRMIST), Kattankulathur 603203, Tamil Nadu, India. Electronic address: kamarajc@srmist.edu.in., Vimal S; Department of Biochemistry, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai 602105, Tamil Nadu, India., Ragavendran C; Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600 077, India., Priyadharsan A; Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600 077, India., Marimuthu K; Department of Environmental Science, Tezpur Univrsity, Napaam, Tezpur, Assam 784028, India. Electronic address: kmmuthu@tezu.ernet.in., Malafaia G; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil. Electronic address: guilhermeifgoiano@gmail.com.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2023 May 15; Vol. 873, pp. 162402. Date of Electronic Publication: 2023 Feb 24.
DOI: 10.1016/j.scitotenv.2023.162402
Abstrakt: It has been shown that vegetal species constitute an alternative natural source for the biosynthesis of new nanomaterials. Thus, aiming to expand knowledge about the potential use of plants in the fabrication of metallic nanomaterials, we aimed to synthesize silver nanoparticles (AgNPs) from phyto-formulation (PF) of ten commonly used medicinal plants. Our results demonstrate the formation of spherical, stable, polycrystalline AgNPs with a diameter of 8.42 nm to 18.40 nm, whose biosynthesis confirmation was performed via UV-Vis spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction analysis (XRD), field emission scanning electron microscopy (FE-SEM)-energy dispersive X-ray spectroscopy (EDS) mapping, high-resolution transmission electron microscopy (HR-TEM), dynamic light scattering (DLS), and zeta potential studies. Furthermore, we demonstrated that the biosynthesized AgNPs showed larvicidal activity against Aedes aegypti and Anopheles stephensi larvae, with the histopathology findings from the fourth instar larval stage validating such larvicidal toxicity. The histological examinations showed severe degradation of the larvae's hindgut, epithelial cells, midgut, and cortical area. However, the PF extract and the biosynthesized AgNPs showed high ecotoxicity in Danio rerio larvae exposed to different concentrations. The treatments induced changes in hatchability percentage, animal growth, and heartbeat. Therefore, despite supporting the potential of PF (from ten plant species) as a raw material source for AgNPs biosynthesis, our study also sheds light on its ecotoxicological potential, suggesting that more comprehensive assessments of the ecotoxicity of biosynthesized would be performed before its application in different sectors.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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