Evaluation of the Antibacterial Properties of Polyvinyl Alcohol-Pullulan Scaffolds Loaded with Nepeta racemosa Lam. Essential Oil and Perspectives for Possible Applications.

Autor: Lungoci C; Department of Plant Science, Iasi University of Life Sciences, 3 Sadoveanu Alley, 700490 Iasi, Romania., Rîmbu CM; Department of Public Health, Iasi University of Life Sciences, 8 Sadoveanu Alley, 707027 Iasi, Romania., Motrescu I; Department of Exact Sciences, Iasi University of Life Sciences, 3 Sadoveanu Alley, 700490 Iasi, Romania.; Research Institute for Agriculture and Environment, Iasi University of Life Sciences, 9 Sadoveanu Alley, 700490 Iasi, Romania., Serbezeanu D; Department of Polycondensation and Thermally Stable Polymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania., Horhogea CE; Department of Public Health, Iasi University of Life Sciences, 8 Sadoveanu Alley, 707027 Iasi, Romania., Vlad-Bubulac T; Department of Polycondensation and Thermally Stable Polymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania., Ghițău CS; Department of Plant Science, Iasi University of Life Sciences, 3 Sadoveanu Alley, 700490 Iasi, Romania., Puiu I; Department of Plant Science, Iasi University of Life Sciences, 3 Sadoveanu Alley, 700490 Iasi, Romania., Neculai-Văleanu AS; Research and Development Station for Cattle Breading Dancu, 9 Iasi-Ungheni rd., 707252 Dancu, Romania., Robu T; Department of Plant Science, Iasi University of Life Sciences, 3 Sadoveanu Alley, 700490 Iasi, Romania.
Jazyk: angličtina
Zdroj: Plants (Basel, Switzerland) [Plants (Basel)] 2023 Feb 16; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 16.
DOI: 10.3390/plants12040898
Abstrakt: Essential oil of Nepeta racemosa Lam. was extracted and characterized to determine its antimicrobial activity and potential use in applications. The essential oil was loaded on polyvinyl alcohol-pullulan films and gels and characterized by optical microscopy, scanning electron microscopy, and UV-Vis spectroscopy before having its antimicrobial capacities assessed. The essential oil extracted from Nepeta racemosa Lam. was characterized using gas chromatography coupled with mass spectroscopy, which indicated that the most abundant component was nepetalic acid (55.5%), followed by eucalyptol (10.7%) and other compounds with concentrations of about 5% or less. The essential oil, as well as the loaded films and gels, exhibited good antibacterial activity on both gram-positive and gram-negative strains, with growth inhibition zones larger in some cases than for gentamicin, indicating excellent premises for using these essential-oil-loaded materials for applications in the food industry or biomedicine.
Databáze: MEDLINE