| Autor: |
Bashir MH; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Korany NS; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Farag DBE; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Abbass MMS; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt.; Stem Cells and Tissue Engineering Research Group, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Ezzat BA; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Hegazy RH; Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt., Dörfer CE; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian Albrechts University, 24105 Kiel, Germany., Fawzy El-Sayed KM; Stem Cells and Tissue Engineering Research Group, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt.; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian Albrechts University, 24105 Kiel, Germany.; Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo 11553, Egypt. |
| Abstrakt: |
Nanocomposite biomaterials combine a biopolymeric matrix structure with nanoscale fillers. These bioactive and easily resorbable nanocomposites have been broadly divided into three groups, namely natural, synthetic or composite, based on the polymeric origin. Preparing such nanocomposite structures in the form of hydrogels can create a three-dimensional natural hydrophilic atmosphere pivotal for cell survival and new tissue formation. Thus, hydrogel-based cell distribution and drug administration have evolved as possible options for bone tissue engineering and regeneration. In this context, nanogels or nanohydrogels, created by cross-linking three-dimensional polymer networks, either physically or chemically, with high biocompatibility and mechanical properties were introduced as promising drug delivery systems. The present review highlights the potential of hydrogels and nanopolymers in the field of craniofacial tissue engineering and bone regeneration. |
