Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland.

Autor: Yu H; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China., Xiong L; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China., Li Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China., Wei Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China., Zhang Q; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China., Li H; Medical School, Kunming University of Science and Technology, Kunming, China., Chen W; Medical School, Kunming University of Science and Technology, Kunming, China. wchen@kust.edu.cn., Ji X; Medical School, Kunming University of Science and Technology, Kunming, China. jixiuling1023@126.com.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Feb 24; Vol. 13 (1), pp. 3250. Date of Electronic Publication: 2023 Feb 24.
DOI: 10.1038/s41598-023-28488-1
Abstrakt: Viruses play important roles in ecosystems by interfering with the central metabolic pathways of the host during infection via the expression of auxiliary metabolic genes (AMGs), altering the productivity of ecosystems and thus affecting geochemical cycling. In this study, the genetic diversity of phosphorus metabolism AMGs phoH, phoU and pstS was investigated by phylogenetic analysis, PCoA analysis, and alpha diversity analysis based on metagenomic data. It was found that the majority of the sequences were unique to Napahai plateau wetland. It was shown that the genetic diversity of phoH, phoU and pstS genes was independent of both habitats and host origins. In addition, the metabolic pathway of AMGs associated with the phosphorus cycling was identified based on metagenomic data. When phosphorus is deficient, virus utilizes AMGs to affect the metabolic pathway, contributing to higher phosphorus levels in the host and facilitating virus survival, replication, and propagation in the host cell.
(© 2023. The Author(s).)
Databáze: MEDLINE
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