Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation.

Autor: Manini C; Department of Pathology, San Giovanni Bosco Hospital, 10154 Turin, Italy.; Department of Sciences of Public Health and Pediatrics, University of Turin, 10124 Turin, Italy., Provenza C; Department of Pathology, San Giovanni Bosco Hospital, 10154 Turin, Italy., Andrés L; Department of Pathology, Cruces University Hospital, 48903 Barakaldo, Spain., Imaz I; Department of Pathology, Cruces University Hospital, 48903 Barakaldo, Spain., Guarch R; Department of Pathology, Hospital Virgen del Camino, 31008 Pamplona, Spain., Nunziata R; Department of Pathology, San Giovanni Bosco Hospital, 10154 Turin, Italy., López JI; Biomarkers in Cancer Unit, Biocruces-Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Jazyk: angličtina
Zdroj: Clinics and practice [Clin Pract] 2023 Feb 16; Vol. 13 (1), pp. 288-296. Date of Electronic Publication: 2023 Feb 16.
DOI: 10.3390/clinpract13010026
Abstrakt: Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problematic if the case includes two carcinomas with similar cytoarchitecture viewed one inside the other under the microscope. We report four cases of this condition in which clear cell renal cell carcinoma is involved, either as a receptor or as a donor, and remark on the difficulties in recognizing some of them. Appropriate clinical-pathological correlation, including a review of the patient's antecedents and radiological exams, would be a great help in routinely identifying tumor-to-tumor metastases.
Databáze: MEDLINE
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