A rare case of vasculitis in cystic fibrosis: A clinical case.
| Autor: | Nasreddine S; Department of Pulmonology-Critical Care, Hotel Dieu de France UHC, St Joseph University, Beirut, Lebanon., Issa M; Department of Pulmonology-Critical Care, Hotel Dieu de France UHC, St Joseph University, Beirut, Lebanon., Bacha ZA; Department of Pulmonology-Critical Care, Hotel Dieu de France UHC, St Joseph University, Beirut, Lebanon. |
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| Jazyk: | angličtina |
| Zdroj: | Respiratory medicine case reports [Respir Med Case Rep] 2023 Jan 27; Vol. 42, pp. 101816. Date of Electronic Publication: 2023 Jan 27 (Print Publication: 2023). |
| DOI: | 10.1016/j.rmcr.2023.101816 |
| Abstrakt: | Introduction: Cystic fibrosis is known to cause serious complications, such as recurrent pulmonary infections, pancreatic insufficiency, and other symptoms related to exocrine gland dysfunction. A rare manifestation of the disease is discussed in this case of a 24-year-old female diagnosed with cystic fibrosis, a purpuric rash was documented during pulmonary infection flares. Skin biopsy shows a leukocytoclastic vasculitis eruption along with infection. Treatment options are limited and not well established. Our patient received a treatment based on colchicine 1mg per day with a total response. The patient was observed during two consecutive pulmonary infection flares separated by a few months, and a total remission without recurrence was found. Conclusion: Considering its efficacy and safety, further scientific research about colchicine and vasculitis in cystic fibrosis should be aimed at in order to define a strong consensus between the disease and this treatment option. Competing Interests: All authors have declined no conflict of interest. (© 2023 The Authors.) |
| Databáze: | MEDLINE |
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