Clinical characteristics and outcomes of hospital-manifested COVID-19 among Brazilians.

Autor:	Delfino-Pereira P; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil. Electronic address: polidelfino@yahoo.com.br., Pires MC; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: magdacpires@gmail.com., Gomes VMR; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Centro Universitário de Belo Horizonte (UniBH), Belo Horizonte, Brazil. Electronic address: vgvirginiagomes@gmail.com., Nogueira MCA; Hospitais da Rede Mater Dei, Belo Horizonte, Brazil. Electronic address: mathnogueira42@gmail.com., Lima MCPB; Universidade Federal de Ouro Preto, Ouro Preto, Brazil. Electronic address: mariaclarapontellobl@gmail.com., Schwarzbold AV; Universidade Federal de Santa Maria/Hospital Universitário/EBSERH, Santa Maria, Brazil. Electronic address: alexvspoa@gmail.com., Maurílio AO; Hospital São João de Deus, São João de Deus, Brazil. Electronic address: amandaoliveira.maurilio@gmail.com., Scotton ALBA; Hospital Regional Antônio Dias, Patos de Minas, Brazil. Electronic address: analuiza.bahia@yahoo.com.br., Costa ASM; Hospitais da Rede Mater Dei, Belo Horizonte, Brazil. Electronic address: andresmc@gmail.com., Farace BL; Hospital Risoleta Tolentino Neves, Belo Horizonte, Brazil. Electronic address: barbarafarace@gmail.com., de Castro BM; Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Electronic address: brunocastro1199@gmail.com., Cimini CCR; Hospital Santa Rosália. R, Teófilo Otoni, Brazil; Mucuri Medical School (FAMMUC), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Teófilo Otoni, Brazil. Electronic address: christiane.cimini@gmail.com., Silveira DV; Hospital Unimed BH, Belo Horizonte, Brazil. Electronic address: danielvez@gmail.com., Ponce D; Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho'. Av. Prof. Mário Rubens Guimarães Montenegro, s/n - UNESP - Campus de Botucatu, Botucatu, Brazil. Electronic address: daniela.ponce@unesp.br., Pereira EC; Hospital SOS Cárdio, Florianópolis, Brazil. Electronic address: elaynepp@yahoo.com.br., Roesch EW; Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Electronic address: eroesch@hcpa.edu.br., Manenti ERF; Hospital Mãe de Deus, Porto Alegre, Brazil. Electronic address: eulermanenti@gmail.com., Cenci EPA; Hospital Universitário Canoas, Canoas, Brazil. Electronic address: assistencial6_hu@centrodepesquisaclinica.com.br., Dos Santos FC; Hospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Porto Alegre, Brazil. Electronic address: fcdsantos86@gmail.com., Anschau F; Hospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Porto Alegre, Brazil. Electronic address: afernando@ghc.com.br., Aranha FG; Hospital SOS Cárdio, Florianópolis, Brazil. Electronic address: fgaranha@icloud.com., Bartolazzi F; Hospital Santo Antônio. Praça Dr. Márcio Carvalho Lopes Filho, Curvelo, Brazil. Electronic address: fredlazzi@hotmail.com., Nascimento GF; Hospital Unimed BH, Belo Horizonte, Brazil. Electronic address: guilhermefagundesn@hotmail.com., Vianna HR; Hospital Universitário Ciências Médicas, Belo Horizonte, Brazil. Electronic address: hrvianna@hotmail.com., d'Arc Lyra Batista J; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Universidade Federal da Fronteira Sul, Chapecó, Brazil; Hospital Regional do Oeste. R. Florianópolis, Chapecó, Brazil. Electronic address: joannalyra@gmail.com., de Alvarenga JC; Fundação Hospitalar do Estado de Minas Gerais (FHEMIG). Cidade Administrativa de Minas Gerais, Belo Horizonte, Brazil. Electronic address: joice-alvarenga@hotmail.com., Carvalho JDSN; Hospital das Clínicas da Universidade Federal de Pernambuco, Recife, Brazil. Electronic address: juliana.nogueira@ufpe.br., Machado-Rugolo J; Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho'. Av. Prof. Mário Rubens Guimarães Montenegro, s/n - UNESP - Campus de Botucatu, Botucatu, Brazil. Electronic address: jr.machado@unesp.br., Ruschel KB; Hospital Mãe de Deus, Porto Alegre, Brazil; Hospital Universitário Canoas, Canoas, Brazil. Electronic address: karenbruschel@gmail.com., Menezes LSM; Hospital Luxemburgo, Belo Horizonte, Brazil; Hospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: luannasmonteiro@gmail.com., de Castro LC; Hospital Bruno Born, Lajeado, Brazil. Electronic address: pharmlucamsc@gmail.com., Nasi LA; Hospital Moinhos de Vento, Porto Alegre, Brazil. Electronic address: lnasi@terra.com.br., Floriani MA; Hospital Moinhos de Vento, Porto Alegre, Brazil. Electronic address: mai.anschau@gmail.com., Souza MD; Hospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: mairadiassouza@gmail.com., Souza-Silva MVR; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: mairavsouza@gmail.com., Carneiro M; Hospital Santa Cruz, Santa Cruz do Sul, Brazil. Electronic address: marceloc@unisc.br., Bicalho MAC; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Fundação Hospitalar do Estado de Minas Gerais (FHEMIG). Cidade Administrativa de Minas Gerais, Belo Horizonte, Brazil. Electronic address: macbicalho@gmail.com., de Godoy MF; Hospital São Lucas PUCRS, Av. Ipiranga, 6690, Porto Alegre, Brazil. Electronic address: mfdegodoy@gmail.com., Guimarães-Júnior MH; Hospital Márcio Cunha, Ipatinga, Brazil. Electronic address: miltonhenriques@yahoo.com.br., Ziegelmann PK; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Hospital Tacchini. R, Bento Gonçalves, Brazil. Electronic address: patriciakz99@gmail.com., Assaf PL; Hospital Metropolitano Doutor Célio de Castro, Belo Horizonte, Brazil. Electronic address: pedro.ledic@hmdcc.com.br., Martelli PJL; Hospital das Clínicas da Universidade Federal de Pernambuco, Recife, Brazil. Electronic address: petroniocarla@uol.com.br., Finger RG; Hospital Regional do Oeste. R. Florianópolis, Chapecó, Brazil. Electronic address: renanfinger@yahoo.com.br., Francisco SC; Hospital Metropolitano Doutor Célio de Castro, Belo Horizonte, Brazil. Electronic address: saionaracf@gmail.com., Araújo SF; Hospital Semper, Belo Horizonte, Brazil. Electronic address: silviaferreiragastro@gmail.com., Oliveira TF; Hospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: talitafischeroliveira@gmail.com., de Oliveira TC; Hospital Universitário Canoas, Canoas, Brazil. Electronic address: thainarastaehler@hotmail.com., Lage TM; Hospital Márcio Cunha, Ipatinga, Brazil. Electronic address: thalitalage@hotmail.com., Muller V; Hospital São Lucas PUCRS, Av. Ipiranga, 6690, Porto Alegre, Brazil. Electronic address: muller.co.vanessa@gmail.com., Ramires YC; Hospital Bruno Born, Lajeado, Brazil. Electronic address: yuri.ramires@gmail.com., Ferrari TCA; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: tferrari@medicina.ufmg.br., Marcolino MS; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: milenamarc@gmail.com.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2023 May; Vol. 130, pp. 31-37. Date of Electronic Publication: 2023 Feb 21.
DOI:	10.1016/j.ijid.2023.02.012
Abstrakt:	Objectives: To analyze the clinical characteristics and outcomes of admitted patients with the hospital- versus community-manifested COVID-19 and to evaluate the risk factors related to mortality in the first population. Methods: This retrospective cohort included consecutive adult patients with COVID-19, hospitalized between March and September 2020. The demographic data, clinical characteristics, and outcomes were extracted from medical records. Patients with hospital-manifested COVID-19 (study group) and those with community-manifested COVID-19 (control group) were matched by the propensity score model. Logistic regression models were used to verify the risk factors for mortality in the study group. Results: Among 7,710 hospitalized patients who had COVID-19, 7.2% developed symptoms while admitted for other reasons. Patients with hospital-manifested COVID-19 had a higher prevalence of cancer (19.2% vs 10.8%) and alcoholism (8.8% vs 2.8%) than patients with community-manifested COVID-19 and also had a higher rate of intensive care unit requirement (45.1% vs 35.2%), sepsis (23.8% vs 14.5%), and death (35.8% vs 22.5%) (P <0.05 for all). The factors independently associated with increased mortality in the study group were increasing age, male sex, number of comorbidities, and cancer. Conclusion: Hospital-manifested COVID-19 was associated with increased mortality. Increasing age, male sex, number of comorbidities, and cancer were independent predictors of mortality among those with hospital-manifested COVID-19 disease. Competing Interests: Declaration of competing interest The authors have no competing interests to declare. (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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