Chronic kidney disease-associated pruritus in patients undergoing hemodialysis: Xerosis and topical therapy.

Autor: Krismi A; Doctoral Study of Medicine and Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Faculty of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia., Danarti R; Department of Dermatology and Venereology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia., Setiabudi IIDPP; Department of Internal Medicine/Geriatry, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia., Wirohadidjojo YW; Department of Dermatology and Venereology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Jazyk: angličtina
Zdroj: Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2023 Apr; Vol. 27 (2), pp. 91-104. Date of Electronic Publication: 2023 Feb 22.
DOI: 10.1111/hdi.13071
Abstrakt: Chronic kidney disease-associated pruritus (CKD-aP) is a common and distressing symptom for patients with CKD and a difficult challenge for nephrologists and dermatologists. Recent results showed the multifactorial nature of the pathophysiology, and therapeutic trials were only successful in certain subsets of patients. The clinical manifestations are varied, with xerosis being the most common dermatological manifestation and correlated with the intensity of CKD-aP. A better understanding of the pathophysiology of xerosis in CKD-aP and appropriate topical treatment could correct xerosis to reduce the intensity of CKD-aP and improve the patient's quality of life.
(© 2023 International Society for Hemodialysis.)
Databáze: MEDLINE
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