[Epidemiology of leptospirosis in the wetlands of Southern Spain].

Autor:	Gómez-Martín MC; Unidad de Protección de la Salud, Distrito Sanitario Aljarafe-Sevilla Norte, Servicio Andaluz de Salud, Centro de Salud Ciudad Expo, Mairena del Aljarafe (Sevilla), España., Rodríguez-Benjumeda LM; Unidad de Prevención, Promoción y Vigilancia de la Salud, Distrito Sanitario Aljarafe-Sevilla Norte, Servicio Andaluz de Salud, Centro de Salud Ciudad Expo, Mairena del Aljarafe (Sevilla), España., de Eguilior-Mestre MC; Unidad de Gestión Clínica de Coria del Río, Distrito Sanitario Aljarafe-Sevilla Norte, Servicio Andaluz de Salud, Centro de Salud Blas Infante, Coria del Río (Sevilla), España., Lozano-Domínguez MC; Unidad de Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva, Hospital Universitario Virgen del Rocío, Servicio Andaluz de Salud, Sevilla, España., Luque-Márquez R; Unidad de Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva, Hospital Universitario Virgen del Rocío, Servicio Andaluz de Salud, Sevilla, España., Jódar-Sánchez F; Departamento de Economía Aplicada (Estadística y Econometría), Facultad de Ciencias Económicas y Empresariales, Universidad de Málaga, Málaga, España., Aznar-Martín J; Unidad de Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva, Hospital Universitario Virgen del Rocío, Servicio Andaluz de Salud, Sevilla, España; Instituto de Investigaciones Biomédicas de Sevilla, IBIS (Universidad de Sevilla, Hospital Universitario Virgen del Rocío, Junta de Andalucía, Consejo Superior de Investigaciones Científicas), Sevilla, España; Departamento de Microbiología, Facultad de Medicina, Universidad de Sevilla, Sevilla, España., Donaire-Granado JA; Unidad de Investigación, Distrito Sanitario Aljarafe-Sevilla Norte, Servicio Andaluz de Salud, Sevilla, España., Luque-Romero LG; Unidad de Investigación, Distrito Sanitario Aljarafe-Sevilla Norte, Servicio Andaluz de Salud, Sevilla, España; Departamento de Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Sevilla, España. Electronic address: luqueluis2@gmail.com.
Jazyk:	Spanish; Castilian
Zdroj:	Gaceta sanitaria [Gac Sanit] 2023 Feb 15; Vol. 37, pp. 102288. Date of Electronic Publication: 2023 Feb 15 (Print Publication: 2023).
DOI:	10.1016/j.gaceta.2023.102288
Abstrakt:	Objective: To find out whether the leptospirosis incidence rate among red swamp crayfish collectors in the harvesting season is higher than in the general population, and to identify risk factors and assess the direct and indirect health costs associated with leptospirosis seroconversion. Method: This study was carried out between 1 July 2017 and 31 March 2018 in the municipality of Isla Mayor (Seville, Spain). It took the form of a prospective cohort study (exposed population: swamp crayfish collectors; non-exposed population: general population). The population was invited to take part in a prevalence study to be conducted using the ELISA qualitative technique, and informed consent was obtained from those who agreed. Negative serology cases were then included in the cohort study. Both cohorts were monitored clinically and symptomatic cases were serology tested. A second serum sample was taken from the swamp crayfish collectors at the end of the monitoring period to detect asymptomatic cases. Serovars were confirmed by microscopic agglutination testing. A bivariate descriptive analysis was carried out and cumulative incidence and relative risk were calculated, with positive serology being taken as the dependent variable. Results: A total of 278 people were included in the study, of whom 92 made up the swamp crayfish collectors cohort and 186 the general population cohort. Women made up 46.8% of the sample, but only 29.3% of the collectors cohort. The mean age was 45.1 (±16.4) years. Nine cases of seroconversion were detected: eight among swamp crayfish collectors and one in the general population. Overall cumulative incidence was therefore 3.2%: 8.7% in the exposed group and 0.5% in the non-exposed group. Relative risk was 16.2% (95% confidence interval: 2.1-127.4). The total cost of medical assistance and illness-related losses associated with leptospirosis was 1568€/case. Conclusions: Leptospirosis in Isla Mayor is strongly associated with red swamp crayfish collecting. It's incidence here is much higher than that reported in studies published in other countries. (Copyright © 2023 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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