SUBFOVEAL CHOROIDAL TUBERCULOMA IN A HEALTHY YOUNG WOMAN CAUSED BY MYCOBACTERIUM BOVIS.

Autor: Schopp MJ; Department of Ophthalmology, Helios HSK, Wiesbaden, Germany., Strzalkowski P, Dithmar S
Jazyk: angličtina
Zdroj: Retinal cases & brief reports [Retin Cases Brief Rep] 2024 May 01; Vol. 18 (3), pp. 323-327.
DOI: 10.1097/ICB.0000000000001377
Abstrakt: Purpose: To describe a case of a macular tuberculoma in a young and healthy woman after developing a tuberculous lymphadenitis caused by Mycobacterium bovis .
Methods: Retrospective case report.
Results: Tuberculous lymphadenitis caused by M. bovis was detected after biopsy and histological examination as well as polymerase chain reaction test testing of cervical lymph nodes in a 20-year-old patient. An interferon gamma was positive. Shortly starting antitubercular therapy, the patient developed visual deterioration caused by a single yellowish subretinal structure in the macula of the right eye. Optical coherence tomography showed a dome-shaped, hyperreflective, subfoveal choroidal lesion with subtle subretinal fluid. Antitubercular therapy with isoniazid, rifampicin, ethambutol, and pyrazinamide was performed, and the deescalation therapy with isoniazid and rifampicin was extended to 7 months. Further examinations showed regression of choroidal tuberculoma to a scar.
Conclusion: This is the first reported case of choroidal tuberculoma after tuberculous lymphadenitis caused by M. bovis .
Databáze: MEDLINE