Preoperative Muscle Biopsy to Assess Motor End Plate Integrity as a Predictor for Successful Nerve Transfer: A Case Report.

Autor: Chen VY; Department of Orthopaedic Surgery, University of California, Irvine, California., Gonzales LP; Department of Orthopaedic Surgery, University of California, Irvine, California., Johnston TR; Department of Orthopaedic Surgery, University of California, Irvine, California., Steward O; Reeve-Irvine Research Center, University of California, Irvine, California., Gupta R; Department of Orthopaedic Surgery, University of California, Irvine, California.; Reeve-Irvine Research Center, University of California, Irvine, California.
Jazyk: angličtina
Zdroj: JBJS case connector [JBJS Case Connect] 2023 Feb 16; Vol. 13 (1). Date of Electronic Publication: 2023 Feb 16 (Print Publication: 2023).
DOI: e22.00569
Abstrakt: Case: A 60-year-old right-hand-dominant man was referred for persistent right deltoid weakness, lateral shoulder numbness, and severe functional deficit 3 months after undergoing proximal humerus open reduction and internal fixation with plate and fibular strut allograft. Deltoid muscle biopsy demonstrated motor end plate (MEP) degeneration. After partial radial-to-axillary nerve transfer, repeat deltoid muscle biopsy revealed successful regeneration of MEPs with reinnervation of deltoid confirmed with postnerve transfer electromyography.
Conclusion: Selective nerve transfer can successfully rescue a denervated target muscle from further degeneration by restoration of healthy MEPs.
Competing Interests: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/C39).
(Copyright © 2023 by The Journal of Bone and Joint Surgery, Incorporated.)
Databáze: MEDLINE