Foreign body reactions related to orofacial esthetic fillers: A systematic review.

Autor: Santos LG; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Jardim LC; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil., Schuch LF; Department of Oral Diagnosis, Piracicaba Dental School, Campinas University, Piracicaba, Brazil., Silveira FM; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.; Molecular Pathology Area, School of Dentistry, Universidad de la República, Montevideo, Uruguay., Wagner VP; Academic Unit of Oral and Maxillofacial Medicine and Pathology, Department of Clinical Dentistry, University of Sheffield, Sheffield, UK., Pires FR; Dental School, Rio de Janeiro State University, Rio de Janeiro, Brazil., Santos JND; Department of Oral Pathology, School of Dentistry, Federal University of Bahia, Salvador, Brazil., Martins MD; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.; Department of Oral Diagnosis, Piracicaba Dental School, Campinas University, Piracicaba, Brazil.
Jazyk: angličtina
Zdroj: Oral diseases [Oral Dis] 2024 Apr; Vol. 30 (3), pp. 855-864. Date of Electronic Publication: 2023 Mar 13.
DOI: 10.1111/odi.14541
Abstrakt: The aim of this study was to systematically review the clinicopathological data regarding foreign body reactions (FBR) related to esthetic procedures in the orofacial region. Electronic searches were performed in six databases and in gray literature using PEO acronym for the review question. Case series and case reports describing FBR related to esthetic procedures in the orofacial region were included. The JBI Critical Appraisal Checklist-University of Adelaide tool was used for measuring the risk of bias. Eighty-six studies reporting 139 cases of FBR were identified. The mean age at diagnosis was 54.12 years (14-85 years), with most of the cases reported in America, North America (n = 42/30.70%) and Latin America (n = 33/23.60%), mainly occurring in women (n = 131/94.40%). Asymptomatic (n = 60/43.40%) nodules (n = 71/50.60%) were the main clinical characteristics. The lower lip represented the most affected anatomical location (n = 28/22.20%), followed by the upper lip (n = 27/21.60%). Surgical removal was the treatment of choice (n = 53/35.70%). Twelve different dermal fillers were reported in the study, and the microscopic characteristics of the cases varied according to the material used. The results based on case series and case reports showed that nodule and swelling were the main clinical characteristics of FBR related to orofacial esthetic fillers. The histological characteristics depended on the type of the filler material used.
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Databáze: MEDLINE