PSS functionalized and stabilized carbon nanodots for specific sensing of iron in biological medium.

Autor: Ghosh M; Amity Institute of Nanotechnology, Amity University Kolkata, Major Arterial Road, AA II, Newtown, Kolkata, West Bengal 700135, India., Dasgupta U; Amity Institute of Nanotechnology, Amity University Kolkata, Major Arterial Road, AA II, Newtown, Kolkata, West Bengal 700135, India., Nayek S; Amity Institute of Environmental Sciences, Amity University Kolkata, Major Arterial Road, AA II, Newtown, Kolkata, West Bengal 700135, India., Saha A; UGC-DAE Consortium for Scientific Research, Kolkata Centre, Plot 8, Block LB, Sector III, Bidhannagar, Kolkata 700 106, India., Bhattacharjee RR; Amity Institute of Nanotechnology, Amity University Kolkata, Major Arterial Road, AA II, Newtown, Kolkata, West Bengal 700135, India. Electronic address: rama.rb@snuniv.ac.in., Chowdhury AD; Amity Institute of Nanotechnology, Amity University Kolkata, Major Arterial Road, AA II, Newtown, Kolkata, West Bengal 700135, India. Electronic address: adchowdhury@kol.amity.edu.
Jazyk: angličtina
Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2023 May 15; Vol. 293, pp. 122445. Date of Electronic Publication: 2023 Feb 06.
DOI: 10.1016/j.saa.2023.122445
Abstrakt: Carbon Quantum Dots (CQDs) are already emerged as an excellent sensing element for its exceptional behavior in fluorescence, biocompatibility, and water dispersibility. However, its poor stability, selectivity and reproducibility in complex medium still be a big problem for its practical application. To overcome this, in the work, we have developed a new type of carbon quantum dot-PSS fluorescent nanocomposites which has been used for specific Fe 3+ detection. The polystyrene sulfonate (PSS) polymer not only stabilize the QDs but also produces specific sites for Fe 3+ to make a co-ordinate complex via Fe 3+ -SO3. The detection limit is calculated as low as 1 ppm which is adequate for measuring Fe 3+ in blood or water samples. The mechanism of the quenching is very specific towards the Fe 3+ ion due to the presence of PSS which makes the sensor selective among other metal ions and possible interferences. The rapid process of sensing, simple instrumentation, and excellent performances in presence of 1 % BSA and serum samples indicates the possible application for diagnostic usage in near future.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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