Silicon nanoparticles as a fluorometric probe for sensitive detection of cyanide ion and its application in C. elegans bio-imaging.

Autor: Alagarasan JK; School of Chemical Engineering, Yeungnam University, Gyeongsan-si, 712-749, South Korea., Shasikala S; Department of Electronics and Instrumentation, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India., Ganesan S; Department of Environmental Engineering and Management, Chaoyang University of Technology, Taichung, 41349, Taiwan., Arunachalam M; Department of Environmental Sciences, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India., Manojkumar U; Department of Environmental Science, School of Energy & Environmental Sciences, Periyar University, Salem, Tamil Nadu, 636011, India., Palaninaicker S; Department of Environmental Science, School of Energy & Environmental Sciences, Periyar University, Salem, Tamil Nadu, 636011, India., Nguyen DD; Department of Environmental Energy Engineering, Kyonggi University, Suwon-si, 16227, Republic of Korea; Faculty of Environmental and Food Engineering, Nguyen Tat Thanh University, 300A Nguyentat Thanh, District 4, Ho Chi Minh City, 755414, Vietnam., Chang SW; Faculty of Environmental and Food Engineering, Nguyen Tat Thanh University, 300A Nguyentat Thanh, District 4, Ho Chi Minh City, 755414, Vietnam., Lee M; School of Chemical Engineering, Yeungnam University, Gyeongsan-si, 712-749, South Korea. Electronic address: mynlee@yu.ac.kr., Lo HM; Department of Environmental Engineering and Management, Chaoyang University of Technology, Taichung, 41349, Taiwan. Electronic address: hmlo@cyut.edu.tw.
Jazyk: angličtina
Zdroj: Environmental research [Environ Res] 2023 May 01; Vol. 224, pp. 115402. Date of Electronic Publication: 2023 Feb 08.
DOI: 10.1016/j.envres.2023.115402
Abstrakt: In recent years, silicon nanoparticles (Si NPs) have been explored as a promising alternative to traditional organic fluorophores in optical sensing and bioimaging applications owing to their exceptional optical properties and negligible toxicity. In this study, water-dispersible Si NPs were prepared from a 3-aminopropyl trimethoxysilane precursor using a facile one-pot process. The as-prepared Si NPs exhibited excitation-wavelength-dependent fluorescence properties and bright green fluorescence at 530 nm upon excitation at 420 nm. The fluorescence properties of Si NPs remained unperturbed under various physiological conditions, such as varying pH, ionic strength, and incubation time. A sensitive fluorometric turn-off sensor for cyanide ion (CN - ) detection was devised based on the unique fluorescence properties of Si NPs. The Si NPs-based detection assay showed a good linear response toward CN - ranging between 0 and 33 μM, with a limit of detection as low as 0.90 nM. Caenorhabditis elegans is used as a model organism to evaluate the in vivo toxicity and molecular imaging capability of Si NPs.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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