Entamoeba gingivalis and Trichomonas tenax: Protozoa parasites living in the mouth.

Autor: Santos JO; Faculdade de Odontologia, Universidade Anhanguera de São Paulo, Av. dos Autonomistas, 1325, CEP 06020-015 Osasco, SP, Brazil., Roldán WH; Laboratório de Investigação Médica 06, Hospital das Clínicas, Faculdade de Medicina Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 470, CEP 05403-000 São Paulo, SP, Brazil. Electronic address: williamroldang@gmail.com.
Jazyk: angličtina
Zdroj: Archives of oral biology [Arch Oral Biol] 2023 Mar; Vol. 147, pp. 105631. Date of Electronic Publication: 2023 Jan 27.
DOI: 10.1016/j.archoralbio.2023.105631
Abstrakt: Objective: This review article aims to summarize the existing data on the history, biology and potential pathogenicity of Entamoeba gingivalis and Trichomonas tenax in periodontal disease, as well as the available techniques for laboratory diagnosis.
Design: A detailed review of scientific literature available up to October 1, 2022 in three databases (PubMed, Scopus and Web of Science) was performed relevant to biology, biochemistry, epidemiology, and experimental studies on infection by E. gingivalis and T. tenax, as well as laboratory techniques for the diagnosis of both protozoa in periodontal diseases.
Results: Accumulated evidence over the decades indicates that the protozoa E. gingivalis and T. tenax are able to interact with host cells and induce inflammation in the periodontal tissue by promoting the expression of pro-inflammatory molecules and the recruitment of neutrophils, contributing to the periodontal disease process. Among the available techniques for the laboratory diagnosis, culture and molecular assays seems to be the best tools for detection of both protozoan parasites.
Conclusions: E. gingivalis and T. tenax are potentially pathogens that colonize the oral cavity of humans and may cause periodontal disease.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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