Ultrasonography-based reference values for the cross-sectional area of the thyroid gland in children and adolescents: The Fukushima Health Management Survey.

Autor:	Ejiri H; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Asano M; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Nakahata N; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Suzuki S; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Thyroid and Endocrinology, Fukushima Medical University School of Medicine, Fukushima, Japan., Sato A; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Nagamine N; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Takahashi C; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Laboratory Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan., Yamaya Y; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Iwadate M; Department of Surgery, Minamisoma Municipal General Hospital, Fukushima, Japan., Matsuzuka T; Department of Head and Neck Surgery and Otolaryngology, Asahi University Hospital, Gifu, Japan., Ohira T; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan., Yasumura S; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Public Health, Fukushima Medical University School of Medicine, Fukushima, Japan., Suzuki S; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Thyroid and Endocrinology, Division of Internal Medicine, Fukushima Medical University Hospital, Fukushima, Japan., Furuya F; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Thyroid and Endocrinology, Fukushima Medical University School of Medicine, Fukushima, Japan., Shimura H; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Department of Laboratory Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan., Suzuki S; Department of Thyroid Therapeutic Surgery, Fukushima Medical University, Fukushima, Japan., Yokoya S; Thyroid and Endocrine Center, Fukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan., Ohto H; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan., Kamiya K; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, Japan.; Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Jazyk:	angličtina
Zdroj:	Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology [Clin Pediatr Endocrinol] 2023; Vol. 32 (1), pp. 52-57. Date of Electronic Publication: 2022 Oct 15.
DOI:	10.1297/cpe.2022-0057
Abstrakt:	We previously described the thyroid volume, which was calculated by measuring the thyroid width, thickness, and longitudinal length using ultrasonography, in children and adolescents. We have proposed a simplified method for quantitatively assessing the thyroid size, to overcome the inaccuracy and challenges in measuring the longitudinal length of the thyroid. Based on measurements of 317,847 (girls: 156,913, boys: 160,934) children and adolescents, we calculated sex-specific means and standard deviations of thyroid width and thickness, and of the cross-sectional area computed by multiplying them, for every age and 0.1 m 2 of body surface area, after ensuring normal distribution with Box-Cox transformation. Multivariate regression analysis revealed that female sex, age, and body surface area were independently associated with areas of each thyroid lobe. Our novel method may be useful in quantitatively assessing the thyroid size, and appropriately diagnosing pathological conditions, such as hypoplasia, atrophy, and enlargement of the thyroid gland, in children and adolescents. Competing Interests: The authors declare no conflict of interest, in relation to this study. HO is a member of the “Department of Mesenchymal Stem Cell Research”, endowed by Alfresa Corporation. (2023©The Japanese Society for Pediatric Endocrinology.)
Databáze:	MEDLINE
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